Interactor 1: KPCA (P17252)
Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Gene: PRKCA

Interactor 2: M3K9 (P80192)
Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)
Gene: MAP3K9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 32814053
Identification Methods two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~Pkinase, Pkinase~Pkinase, Pkinase~Pkinase_C
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006468 - protein phosphorylation
GO:0106310 - protein serine kinase activity
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 672
Hs

1 1104
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024