Interactor 1: KPCA (P17252)
Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Gene: PRKCA

Interactor 2: TIAM1 (Q13009)
Rho guanine nucleotide exchange factor TIAM1 (T-lymphoma invasion and metastasis-inducing protein 1) (TIAM-1)
Gene: TIAM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 10212259
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~PH, C1_1~RBD, C1_1~RhoGEF, PH~Pkinase
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030335 - positive regulation of cell migration
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 672
Hs

1 1591
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024