HitPredict

Interactor 1: K2C5 (P13647)
Keratin, type II cytoskeletal 5 (58 kDa cytokeratin) (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (Type-II keratin Kb5)
Gene: KRT5

Interactor 2: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 590 Hs			1 1278
+	Hs
		551553 K2C3_HUMAN (140-484): 3.96e-178: 519: 78.10		DCTN1_HUMAN (1-1278): 7.7e-92: 325: 100.00
+	Hs
		777462 K22E_HUMAN (140-484): 3.02e-174: 509: 71.88		DCTN1_HUMAN (1-1278): 7.7e-92: 325: 100.00
+	Hs
		437169 K2C8_HUMAN (140-516): 9.22e-163: 474: 69.23		DCTN1_HUMAN (1-1278): 7.7e-92: 325: 100.00
+	Hs
		1123837 KRT84_HUMAN (1-569): 3.5e-104: 328: 50.96		DCTN1_HUMAN (1-1278): 7.7e-92: 325: 100.00
+	Hs
		341770 K2C75_HUMAN (1-567): 1.14e-102: 323: 70.02		DCTN1_HUMAN (1-1278): 7.7e-92: 325: 100.00
+	Hs
		407288 K2C6B_HUMAN (2-505): 1.51e-89: 289: 79.56		DCTN1_HUMAN (1-1278): 7.7e-92: 325: 100.00
+	Hs
		876468 K2C6C_HUMAN (2-505): 3.09e-89: 288: 79.17		DCTN1_HUMAN (1-1278): 7.7e-92: 325: 100.00
+	Hs
		385271 K2C6A_HUMAN (2-505): 1.61e-85: 278: 79.17		DCTN1_HUMAN (1-1278): 7.7e-92: 325: 100.00
+	Hs
		1030983 K22O_HUMAN (1-496): 2.12e-73: 248: 62.74		DCTN1_HUMAN (1-1278): 7.7e-92: 325: 100.00
+	Hs
		437071 K2C8_HUMAN (140-516): 9.22e-163: 474: 69.23		MYH1_HUMAN (724-1276): 7.88e-17: 88.7: 10.99
+	Hs
		437082 K2C8_HUMAN (140-516): 9.22e-163: 474: 69.23		DESP_HUMAN (227-1049): 1.37e-14: 81.5: 14.64
+	Mm
		98052 K22E_MOUSE (140-506): 1.05e-158: 472: 64.58		DESP_MOUSE (177-1018): 4.46e-14: 80: 13.33
+	Hs
		566397 K2C5_HUMAN (1-590): 1.3e-98: 313: 100.00		MRCKA_HUMAN (154-593): 9.19e-20: 98.4: 15.64
+	Hs
		566326 K2C5_HUMAN (1-590): 1.3e-98: 313: 100.00		DESP_HUMAN (227-1049): 1.37e-14: 81.5: 14.64
+	Hs
		385233 K2C6A_HUMAN (2-505): 1.61e-85: 278: 79.17		DESP_HUMAN (227-1049): 1.37e-14: 81.5: 14.64