Interactor 1: SKI3 (P17883)
Superkiller protein 3
Gene: SKI3

Interactor 2: SKI2 (P35207)
Antiviral helicase SKI2 (EC 3.6.4.13) (Superkiller protein 2)
Gene: SKI2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 16043509, 16429126, 27980209, 18042677, 10744028, 16554755, 37968396
Identification Methods two hybrid, affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation, comigration in gel electrophoresis, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~TPR_8, DSHCT~TPR_8, Ski2_N~TPR_8
Common GO terms GO:0006402 - mRNA catabolic process
GO:0051607 - defense response to virus
GO:0055087 - Ski complex
GO:0070478 - nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
GO:0070481 - nuclear-transcribed mRNA catabolic process, non-stop decay
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1432
Sc

1 1287
+ Hs
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024