HitPredict

Interactor 1: LEG3 (P17931)
Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)
Gene: LGALS3

Interactor 2: IL31R (Q8NI17)
Interleukin-31 receptor subunit alpha (IL-31 receptor subunit alpha) (IL-31R subunit alpha) (IL-31R-alpha) (IL-31RA) (Cytokine receptor-like 3) (GLM-R) (hGLM-R) (Gp130-like monocyte receptor) (Gp130-like receptor) (ZcytoR17)
Gene: IL31RA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 250 Hs			1 732
+	Hs
		572370 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		SDK2_HUMAN (4-700): 5.55e-33: 139: 8.66
+	Hs
		572394 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		SDK1_HUMAN (7-708): 1.18e-31: 135: 8.95
+	Hs
		449334 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		NEO1_HUMAN (23-715): 6.59e-60: 221: 12.57
+	Hs
		265746 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		CRLF1_HUMAN (18-230): 4.51e-59: 207: 26.91
+	Hs
		814965 LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04		SDK2_HUMAN (4-700): 5.55e-33: 139: 8.66
+	Hs
		814978 LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04		SDK1_HUMAN (7-708): 1.18e-31: 135: 8.95
+	Hs
		449281 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		SDK2_HUMAN (4-700): 5.55e-33: 139: 8.66
+	Hs
		449306 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		SDK1_HUMAN (7-708): 1.18e-31: 135: 8.95
+	Hs
		121183 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		SDK1_HUMAN (7-708): 1.18e-31: 135: 8.95
+	Hs
		449332 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		NRCAM_HUMAN (32-670): 1.45e-25: 115: 10.38
+	Hs
		449213 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		IL6RB_HUMAN (5-321): 4.37e-20: 97.4: 12.35
+	Hs
		449192 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		PTPRD_HUMAN (1-268): 3.22e-17: 88.9: 13.41
+	Hs
		449205 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		L1CAM_HUMAN (25-406): 1.19e-09: 63.9: 11.11