HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: TOM71 (P38825)
Protein TOM71 (71 kDa mitochondrial outer membrane protein)
Gene: TOM71

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37295430
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HSP90~TPR_1, HSP90~TPR_8
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 705 Sc			1 639
+	Sc
		451988 HSC82_YEAST (1-705): 0: 971: 100.00		TOM70_YEAST (6-639): 2.3e-69: 238: 47.99
+	Sc
		392005 HSP82_YEAST (1-705): 0: 963: 95.63		TOM70_YEAST (6-639): 2.3e-69: 238: 47.99
+	Hs
		468210 HS90B_HUMAN (5-705): 0: 1016: 61.15		PPP5_HUMAN (109-385): 3.64e-35: 141: 20.00
+	Mm
		547256 HS90B_MOUSE (5-705): 0: 1019: 61.57		PPP5_MOUSE (109-234): 5.83e-34: 137: 28.79
+	Hs
		117618 K9JA46_HUMAN (4-705): 0: 1007: 60.67		PPP5_HUMAN (109-385): 3.64e-35: 141: 20.00
+	Hs
		461300 HS90A_HUMAN (4-705): 0: 1007: 60.67		PPP5_HUMAN (109-385): 3.64e-35: 141: 20.00
+	Mm
		462116 HS90A_MOUSE (4-705): 0: 1005: 60.59		PPP5_MOUSE (109-234): 5.83e-34: 137: 28.79
+	Hs
		461856 HS90A_HUMAN (4-705): 0: 1007: 60.67		TTC1_HUMAN (39-279): 1.14e-28: 118: 19.36
+	Hs
		185366 HS90B_HUMAN (5-705): 0: 1016: 61.15		OGT1_HUMAN (34-348): 1.87e-23: 107: 8.70
+	Hs
		317976 HS90B_HUMAN (5-705): 0: 1016: 61.15		TOM70_HUMAN (159-627): 3.62e-23: 106: 13.57
+	Hs
		185361 HS90A_HUMAN (4-705): 0: 1007: 60.67		OGT1_HUMAN (34-348): 1.87e-23: 107: 8.70
+	Hs
		317975 HS90A_HUMAN (4-705): 0: 1007: 60.67		TOM70_HUMAN (159-627): 3.62e-23: 106: 13.57
+	Hs
		461421 HS90A_HUMAN (4-705): 0: 1007: 60.67		IFT88_HUMAN (30-364): 3.53e-15: 81.2: 9.85
+	Hs
		461397 HS90A_HUMAN (4-705): 0: 1007: 60.67		SPAG1_HUMAN (235-465): 1.88e-13: 75.9: 11.69
+	Hs
		468113 HS90B_HUMAN (5-705): 0: 1016: 61.15		STIP1_HUMAN (49-306): 6.32e-09: 60.8: 10.56
+	Dm
		391918 HSP83_DROME (3-705): 0: 991: 59.58		Q9VPN5_DROME (115-414): 2.04e-15: 81.2: 14.98
+	Hs
		117617 K9JA46_HUMAN (4-705): 0: 1007: 60.67		STIP1_HUMAN (49-306): 6.32e-09: 60.8: 10.56
+	Hs
		461192 HS90A_HUMAN (4-705): 0: 1007: 60.67		STIP1_HUMAN (49-306): 6.32e-09: 60.8: 10.56
+	At
		938316 HS902_ARATH (3-705): 0: 977: 63.93		HSOP2_ARATH (377-489): 1.17e-12: 72.8: 15.93
+	Sc
		578768 HSC82_YEAST (1-705): 0: 971: 100.00		STI1_YEAST (62-371): 2.28e-14: 78.5: 15.14