Protein: TOM70
Mitochondrial import receptor subunit TOM70 (70 kDa mitochondrial outer membrane protein) (Translocase of outer membrane 70 kDa subunit)

Gene: TOM70
Organism: Saccharomyces cerevisiae S288C
Interactions: 98
UniProt ID: P07213

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005742 - mitochondrial outer membrane translocase complex
GO:0006626 - protein targeting to mitochondrion
GO:0015450 - protein-transporting ATPase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

451985

HSP71
Heat shock protein SSA1

5

20

Small-scale

0.906

High

451986

HSP72
Heat shock protein SSA2

3

20

Small-scale

0.818

High

392005

HSP82
ATP-dependent molecular chaperone HSP82

2

20

Small-scale

0.778

High

451979

TOM70
Mitochondrial import receptor subunit TOM70

2

18

Small-scale

0.778

High

451990

STI1
Heat shock protein STI1

2

19

Small-scale

0.778

High

451992

TOM40
Mitochondrial import receptor subunit TOM40

8

2

Small-scale

0.741

High

452036

TOM22
Mitochondrial import receptor subunit TOM22

5

1

Small-scale

0.712

High

452003

HSP7F
Heat shock protein homolog SSE1

2

20

High-throughput

0.637

High

452009

TOM20
Mitochondrial import receptor subunit TOM20

2

3

Small-scale

0.631

High

451984

HSP77
Import motor subunit, mitochondrial

1

20

High-throughput

0.618

High

451988

HSC82
ATP-dependent molecular chaperone HSC82

1

20

High-throughput

0.618

High

452012

MIC60
MICOS complex subunit MIC60

3

0

Small-scale

0.606

High

451994

MAS5
Mitochondrial protein import protein MAS5

2

14

Small-scale

0.602

High

451993

SIS1
Protein SIS1

3

20

Small-scale

0.594

High

451999

HS104
Heat shock protein 104

3

6

Small-scale

0.585

High

452029

DJP1
DnaJ-like protein 1

2

20

Small-scale

0.585

High

451991

ADT2
ADP,ATP carrier protein 2

2

6

Small-scale

0.584

High

452007

HSP78
Heat shock protein 78, mitochondrial

2

5

High-throughput

0.584

High

452032

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

11

High-throughput

0.584

High

452004

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

2

2

Small-scale

0.571

High

399770

COX4
Cytochrome c oxidase subunit 4, mitochondrial

2

0

Small-scale

0.569

High

452058

MIM1
Mitochondrial import protein 1

2

0

Small-scale

0.559

High

440994

KAPA
cAMP-dependent protein kinase type 1

2

9

Small-scale

0.550

High

452000

OAC1
Mitochondrial oxaloacetate transport protein

1

7

High-throughput

0.541

High

452046

ALO
D-arabinono-1,4-lactone oxidase

1

2

High-throughput

0.541

High

452052

UGO1
Mitochondrial fusion and transport protein UGO1

1

0

Small-scale

0.537

High

451981

PT111
Protein PET111, mitochondrial

1

0

High-throughput

0.518

High

451987

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.514

High

451980

ATPA
ATP synthase subunit alpha, mitochondrial

1

10

Small-scale

0.501

High

452059

PSK2
Serine/threonine-protein kinase PSK2

1

9

High-throughput

0.501

High

452015

MAL31
Maltose permease MAL31

1

1

High-throughput

0.494

High

452028

TOK1
Outward-rectifier potassium channel TOK1

1

1

High-throughput

0.494

High

452056

ANT1
Peroxisomal adenine nucleotide transporter 1

1

5

High-throughput

0.494

High

452019

OM14
Mitochondrial outer membrane protein OM14

1

1

Small-scale

0.481

High

452038

JAC1
J-type co-chaperone JAC1, mitochondrial

1

0

Small-scale

0.480

High

452066

EMR1
ERMES regulator 1

1

0

Small-scale

0.480

High

416986

VDAC1
Non-selective voltage-gated ion channel 1

1

3

Small-scale

0.479

High

451996

MSP1
Outer mitochondrial transmembrane helix translocase

1

16

Small-scale

0.479

High

452011

MCR1
NADH-cytochrome b5 reductase 2

1

5

High-throughput

0.479

High

452045

SAM50
Sorting assembly machinery 50 kDa subunit

1

3

High-throughput

0.479

High

452051

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

1

Small-scale

0.479

High

452057

LAM6
Membrane-anchored lipid-binding protein LAM6

1

2

Small-scale

0.479

High

452060

YD157
Uncharacterized protein YDL157C, mitochondrial

1

1

Small-scale

0.479

High

452065

SMC6
Structural maintenance of chromosomes protein 6

1

9

High-throughput

0.479

High

382781

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

399905

COX8
Cytochrome c oxidase subunit 8, mitochondrial

1

0

Small-scale

0.458

High

452005

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.458

High

452008

TOM6
Mitochondrial import receptor subunit TOM6

1

0

Small-scale

0.458

High

452013

QCR10
Cytochrome b-c1 complex subunit 10, mitochondrial

1

0

Small-scale

0.458

High

452018

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

452023

PSD1
Phosphatidylserine decarboxylase proenzyme 1, mitochondrial

1

0

Small-scale

0.458

High

452027

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

0

High-throughput

0.458

High

452040

TOM7
Mitochondrial import receptor subunit TOM7

1

0

Small-scale

0.458

High

452049

TOM5
Mitochondrial import receptor subunit TOM5

1

0

Small-scale

0.458

High

452054

CIS1
Citrinin resistance protein, mitochondrial

1

0

Small-scale

0.458

High

451995

KCC1
Calcium/calmodulin-dependent protein kinase I

1

9

High-throughput

0.457

High

452034

IKS1
Probable serine/threonine-protein kinase IKS1

1

8

High-throughput

0.457

High

452053

ISR1
Serine/threonine-protein kinase ISR1

1

1

High-throughput

0.457

High

452061

HSP42
Heat shock protein 42

1

1

Small-scale

0.457

High

452064

AHA1
Hsp90 co-chaperone AHA1

1

5

Small-scale

0.457

High

366882

ATPB
ATP synthase subunit beta, mitochondrial

1

10

High-throughput

0.445

High

452010

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

2

Small-scale

0.445

High

416177

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

7

High-throughput

0.437

High

451989

SYKC
Lysine--tRNA ligase, cytoplasmic

1

8

High-throughput

0.437

High

451998

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

452001

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.437

High

452006

SRPR
Signal recognition particle receptor subunit alpha homolog

1

3

High-throughput

0.437

High

452014

ANM1
Protein arginine N-methyltransferase 1

1

9

High-throughput

0.437

High

452016

NU170
Nucleoporin NUP170

1

3

High-throughput

0.437

High

452020

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

8

High-throughput

0.437

High

452021

YHI0
Putative proline--tRNA ligase YHR020W

1

9

High-throughput

0.437

High

452033

SFH5
Phosphatidylinositol transfer protein SFH5

1

1

High-throughput

0.437

High

452037

SKP1
Suppressor of kinetochore protein 1

1

1

Small-scale

0.437

High

452039

PESC
Pescadillo homolog

1

1

High-throughput

0.437

High

452041

SPC98
Spindle pole body component SPC98

1

5

High-throughput

0.437

High

452042

HST2
NAD-dependent protein deacetylase HST2

1

1

High-throughput

0.437

High

452043

ATP23
Mitochondrial inner membrane protease ATP23

1

1

High-throughput

0.437

High

452050

TIM10
Mitochondrial import inner membrane translocase subunit TIM10

1

0

Small-scale

0.426

High

451982

TBA1
Tubulin alpha-1 chain

1

17

High-throughput

0.407

High

452024

TCPZ
T-complex protein 1 subunit zeta

1

11

High-throughput

0.407

High

452048

SLG1
Protein SLG1

2

0

Small-scale

0.320

High

452017

FUI1
Uridine permease

1

0

High-throughput

0.282

High

452030

SYS1
Protein SYS1

1

0

High-throughput

0.282

High

452047

HXT15
Hexose transporter HXT15

1

0

High-throughput

0.282

High

451997

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

452002

MET4
Transcriptional activator of sulfur metabolism MET4

1

0

High-throughput

0.249

Low

452025

SS120
Protein SSP120

1

0

High-throughput

0.249

Low

452026

PFD2
Prefoldin subunit 2

1

0

Small-scale

0.249

Low

452031

EMP47
Protein EMP47

1

0

High-throughput

0.249

Low

452035

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

452044

PDR16
Phosphatidylinositol transfer protein PDR16

1

0

High-throughput

0.249

Low

452055

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

452063

EMC6
ER membrane protein complex subunit 6

1

0

High-throughput

0.249

Low

452067

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

451983

YB39B
Uncharacterized protein YBL039W-B

1

0

High-throughput

0.238

Low

452022

YHS2
MIP18 family protein YHR122W

1

0

High-throughput

0.238

Low

452062

ATG31
Autophagy-related protein 31

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025