HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0015629 - actin cytoskeleton GO:0045296 - cadherin binding GO:0051015 - actin filament binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 586 Hs			1 1025
+	Hs
		767457 RADI_HUMAN (1-586): 7.86e-165: 484: 76.28		MPRIP_HUMAN (1-1025): 9.69e-126: 410: 100.00
+	Hs
		583007 EZRI_HUMAN (1-586): 5.69e-178: 517: 100.00		SWP70_HUMAN (370-824): 7.3e-58: 212: 19.22
+	Hs
		582891 EZRI_HUMAN (1-586): 5.69e-178: 517: 100.00		DLG5_HUMAN (647-1019): 8.92e-54: 207: 21.61
+	Hs
		767474 RADI_HUMAN (1-586): 7.86e-165: 484: 76.28		DLG5_HUMAN (647-1019): 8.92e-54: 207: 21.61
+	Hs
		582841 EZRI_HUMAN (1-586): 5.69e-178: 517: 100.00		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		582965 EZRI_HUMAN (1-586): 5.69e-178: 517: 100.00		PKHA5_HUMAN (318-1019): 2.96e-36: 151: 13.24
+	Hs
		767453 RADI_HUMAN (1-586): 7.86e-165: 484: 76.28		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		582836 EZRI_HUMAN (1-586): 5.69e-178: 517: 100.00		MRCKA_HUMAN (418-981): 1.19e-30: 133: 12.40
+	Hs
		767323 MERL_HUMAN (2-586): 3.19e-146: 436: 44.37		SCAPE_HUMAN (71-938): 5.41e-44: 176: 13.60
+	Hs
		1234966 E41L5_HUMAN (5-586): 7.73e-142: 430: 21.28		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		582956 EZRI_HUMAN (1-586): 5.69e-178: 517: 100.00		TARA_HUMAN (645-1023): 9.99e-10: 65.1: 12.98
+	Hs
		683785 MOES_HUMAN (1-586): 4.47e-161: 474: 72.70		MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35
+	Hs
		1234955 E41L1_HUMAN (3-524): 3.55e-119: 375: 23.06		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		1235048 FARP1_HUMAN (3-549): 1.98e-117: 375: 19.07		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		217457 E41L2_HUMAN (2-577): 1.06e-117: 374: 19.70		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		538892 EPB41_HUMAN (3-553): 9.59e-129: 400: 22.99		MYH10_HUMAN (242-1024): 1.66e-21: 103: 8.45
+	Hs
		1431712 E41L5_HUMAN (5-586): 7.73e-142: 430: 21.28		TARA_HUMAN (645-1023): 9.99e-10: 65.1: 12.98
+	Hs
		538891 EPB41_HUMAN (3-553): 9.59e-129: 400: 22.99		MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35
+	Hs
		538862 EPB41_HUMAN (3-553): 9.59e-129: 400: 22.99		MYH1_HUMAN (515-1019): 1.69e-12: 74.4: 13.23
+	Hs
		708853 PTN4_HUMAN (4-480): 1.14e-123: 388: 22.20		PLEC_HUMAN (499-978): 3.11e-11: 70.1: 14.96