HitPredict

Interactor 1: TFE2 (P15923)
Transcription factor E2-alpha (Class B basic helix-loop-helix protein 21) (bHLHb21) (Immunoglobulin enhancer-binding factor E12/E47) (Immunoglobulin transcription factor 1) (Kappa-E2-binding factor) (Transcription factor 3) (TCF-3) (Transcription factor ITF-1)
Gene: TCF3

Interactor 2: TCF24 (Q7RTU0)
Transcription factor 24 (TCF-24)
Gene: TCF24

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22354994
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 654 Hs			1 167
+	Hs
		561205 TFE2_HUMAN (1-654): 0: 907: 100.00		MYF5_HUMAN (14-165): 2.18e-32: 117: 17.76
+	Hs
		581617 TFE2_HUMAN (1-654): 0: 907: 100.00		MYOD1_HUMAN (6-167): 3.11e-31: 116: 18.71
+	Hs
		587467 TFE2_HUMAN (1-654): 0: 907: 100.00		NDF1_HUMAN (40-167): 8.55e-30: 112: 23.49
+	Hs
		587494 TFE2_HUMAN (1-654): 0: 907: 100.00		TCF23_HUMAN (26-146): 4.44e-30: 110: 59.84
+	Hs
		587507 TFE2_HUMAN (1-654): 0: 907: 100.00		TWST2_HUMAN (13-136): 6.11e-29: 106: 24.19
+	Hs
		354051 TFE2_HUMAN (1-654): 0: 907: 100.00		HAND1_HUMAN (26-119): 3.69e-28: 105: 40.43
+	Hs
		587492 TFE2_HUMAN (1-654): 0: 907: 100.00		PTF1A_HUMAN (6-108): 3.6e-27: 105: 29.57
+	Hs
		587477 TFE2_HUMAN (1-654): 0: 907: 100.00		TWST1_HUMAN (8-136): 7.98e-28: 104: 27.13
+	Hs
		558951 TFE2_HUMAN (1-654): 0: 907: 100.00		LYL1_HUMAN (15-130): 7.93e-26: 101: 31.03
+	Hs
		587512 TFE2_HUMAN (1-654): 0: 907: 100.00		ATOH1_HUMAN (31-127): 5.93e-25: 100: 28.87
+	Hs
		223955 TFE2_HUMAN (1-654): 0: 907: 100.00		TCF21_HUMAN (13-155): 2.74e-26: 99.8: 34.03
+	Hs
		253535 TFE2_HUMAN (1-654): 0: 907: 100.00		MUSC_HUMAN (14-155): 1.06e-25: 99.1: 33.57
+	Hs
		587436 TFE2_HUMAN (1-654): 0: 907: 100.00		HAND2_HUMAN (4-123): 1.63e-25: 99.1: 32.80
+	Hs
		587513 TFE2_HUMAN (1-654): 0: 907: 100.00		NGN1_HUMAN (3-140): 4.81e-25: 98.3: 24.64
+	Hs
		587501 TFE2_HUMAN (1-654): 0: 907: 100.00		ATOH7_HUMAN (1-149): 2.54e-25: 96.8: 30.32
+	Hs
		587480 TFE2_HUMAN (1-654): 0: 907: 100.00		TAL2_HUMAN (48-156): 3.5e-25: 94.8: 22.94
+	Hs
		587450 TFE2_HUMAN (1-654): 0: 907: 100.00		HEN1_HUMAN (51-105): 2.1e-24: 93.8: 49.09
+	Hs
		587451 TFE2_HUMAN (1-654): 0: 907: 100.00		HEN2_HUMAN (52-105): 2.03e-22: 88.8: 50.00
+	Hs
		587461 TFE2_HUMAN (1-654): 0: 907: 100.00		TCF15_HUMAN (50-105): 4.27e-15: 71: 44.64
+	Hs
		587495 TFE2_HUMAN (1-654): 0: 907: 100.00		SCX_HUMAN (50-105): 5.16e-14: 68.3: 41.07