HitPredict

Interactor 1: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Interactor 2: WDR6 (Q9NNW5)
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WD repeat-containing protein 6)
Gene: WDR6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27609421
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 968 Hs			1 1121
+	Hs
		883648 RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00		WDR6_HUMAN (1-1121): 0: 745: 100.00
+	Hs
		587512 NFKB1_HUMAN (1-968): 0: 796: 100.00		RACK1_HUMAN (196-523): 2.91e-47: 173: 17.21
+	Hs
		587758 NFKB1_HUMAN (1-968): 0: 796: 100.00		FBW1A_HUMAN (30-284): 7.71e-34: 140: 13.41
+	Hs
		587745 NFKB1_HUMAN (1-968): 0: 796: 100.00		FBW1B_HUMAN (258-535): 1.92e-29: 126: 13.88
+	Hs
		587665 NFKB1_HUMAN (1-968): 0: 796: 100.00		FBXW7_HUMAN (603-914): 3.98e-13: 76: 13.75
+	Hs
		978943 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		FBW1A_HUMAN (30-284): 7.71e-34: 140: 13.41
+	Hs
		978930 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		FBW1B_HUMAN (258-535): 1.92e-29: 126: 13.88
+	Hs
		981788 REL_HUMAN (35-484): 6.21e-110: 354: 33.91		FBW1A_HUMAN (30-284): 7.71e-34: 140: 13.41
+	Hs
		964515 RELB_HUMAN (30-459): 1.19e-121: 384: 33.10		FBXW7_HUMAN (603-914): 3.98e-13: 76: 13.75
+	Hs
		978839 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		FBXW7_HUMAN (603-914): 3.98e-13: 76: 13.75
+	Hs
		883474 RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00		RACK1_HUMAN (196-523): 2.91e-47: 173: 17.21
+	Hs
		639829 IKBA_HUMAN (485-767): 1.18e-66: 228: 35.45		FBW1A_HUMAN (30-284): 7.71e-34: 140: 13.41
+	Hs
		883676 RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00		FBW1A_HUMAN (30-284): 7.71e-34: 140: 13.41
+	Hs
		639819 IKBA_HUMAN (485-767): 1.18e-66: 228: 35.45		FBW1B_HUMAN (258-535): 1.92e-29: 126: 13.88
+	Hs
		72802 RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00		B4DH70_HUMAN (258-535): 1.78e-29: 126: 13.88
+	Hs
		883666 RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00		FBW1B_HUMAN (258-535): 1.92e-29: 126: 13.88
+	Hs
		639784 IKBA_HUMAN (485-767): 1.18e-66: 228: 35.45		FBXW7_HUMAN (603-914): 3.98e-13: 76: 13.75
+	Mm
		222603 IKBE_MOUSE (541-766): 1.03e-33: 135: 38.20		FBW1A_MOUSE (30-284): 8.67e-34: 140: 13.41
+	Mm
		1112935 IKBA_MOUSE (541-767): 9.47e-33: 131: 40.00		FBW1A_MOUSE (30-284): 8.67e-34: 140: 13.41
+	Mm
		1131318 IKBA_MOUSE (541-767): 9.47e-33: 131: 40.00		FBW1B_MOUSE (258-535): 1.05e-29: 127: 13.88