HitPredict

Interactor 1: MET (P16056)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	27086544
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0007268 - chemical synaptic transmission GO:0016020 - membrane GO:0098794 - postsynapse
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1379 Mm			1 724
+	Hs
		472058 MET_HUMAN (1-1379): 0: 1324: 89.50		SCRIB_HUMAN (58-243): 7.61e-25: 113: 40.72
+	Hs
		1006068 ERBB4_HUMAN (1080-1338): 2.5e-52: 204: 42.42		DLG4_HUMAN (1-724): 0: 653: 99.59
+	Mm
		1222817 ERBB4_MOUSE (1080-1338): 1.6e-52: 204: 42.42		DLG4_MOUSE (1-724): 0: 653: 100.00
+	Hs
		1145761 ERBB4_HUMAN (1080-1338): 2.5e-52: 204: 42.42		DLG3_HUMAN (28-724): 0: 583: 63.81
+	Hs
		168659 EPHA4_HUMAN (576-1368): 1.7e-170: 536: 17.67		CSKP_HUMAN (6-203): 2.92e-19: 94.7: 14.08
+	Hs
		931842 EPHA5_HUMAN (576-1364): 6.98e-172: 542: 19.43		DLG1_HUMAN (174-402): 2.77e-17: 88.6: 20.90
+	Hs
		932062 EPHA4_HUMAN (576-1368): 1.7e-170: 536: 17.67		DLG1_HUMAN (174-402): 2.77e-17: 88.6: 20.90
+	Hs
		710831 EPHB2_HUMAN (1019-1340): 4.25e-103: 355: 32.82		SCRIB_HUMAN (58-243): 7.61e-25: 113: 40.72
+	Hs
		650129 FGFR3_HUMAN (980-1358): 5.01e-105: 354: 32.08		EM55_HUMAN (6-171): 6.21e-19: 92.4: 19.16
+	Hs
		650293 FGFR3_HUMAN (980-1358): 5.01e-105: 354: 32.08		PALS1_HUMAN (52-184): 5.33e-13: 74.3: 14.93
+	Hs
		720218 UFO_HUMAN (1076-1331): 8.47e-66: 243: 45.90		SCRIB_HUMAN (58-243): 7.61e-25: 113: 40.72
+	Hs
		720208 UFO_HUMAN (1076-1331): 8.47e-66: 243: 45.90		DLG1_HUMAN (174-402): 2.77e-17: 88.6: 20.90
+	Hs
		465517 IGF1R_HUMAN (1082-1335): 7.6e-57: 218: 42.16		SCRIB_HUMAN (58-243): 7.61e-25: 113: 40.72
+	Hs
		1145735 ERBB4_HUMAN (1080-1338): 2.5e-52: 204: 42.42		DLG2_HUMAN (225-570): 1.44e-17: 89.3: 17.32
+	Hs
		1091498 ERBB4_HUMAN (1080-1338): 2.5e-52: 204: 42.42		DLG1_HUMAN (174-402): 2.77e-17: 88.6: 20.90
+	Rn
		92830 INSR_RAT (1082-1333): 1.99e-52: 204: 40.98		MPP2_RAT (2-383): 2.13e-17: 88.2: 16.50