HitPredict

Interactor 1: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Interactor 2: PEAK1 (Q9H792)
Inactive tyrosine-protein kinase PEAK1 (Pseudopodium-enriched atypical kinase 1) (Sugen kinase 269) (Tyrosine-protein kinase SgK269)
Gene: PEAK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Hs			1 1746
+	Hs
		222208 NCK2_HUMAN (1-376): 1.95e-92: 283: 68.24		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		834230 CSK_HUMAN (186-375): 1.98e-33: 131: 26.18		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		987945 GRB2_HUMAN (3-61): 2.31e-17: 82.1: 28.81		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Mm
		1221227 GRB2_MOUSE (3-61): 2.57e-17: 81.8: 28.81		PEAK1_MOUSE (1-1746): 0: 2159: 85.76
+	Hs
		728082 CSK_HUMAN (186-375): 1.98e-33: 131: 26.18		AKT1_HUMAN (1362-1695): 4.45e-91: 307: 15.07
+	Mm
		591034 P70304_MOUSE (241-376): 9.1e-23: 102: 19.57		KPCE_MOUSE (1352-1719): 4.42e-92: 318: 13.12
+	Hs
		440402 FYN_HUMAN (7-164): 5.43e-24: 105: 17.50		AKT1_HUMAN (1362-1695): 4.45e-91: 307: 15.07
+	Hs
		699609 P85A_HUMAN (241-376): 5.42e-23: 102: 19.57		AKT1_HUMAN (1362-1695): 4.45e-91: 307: 15.07
+	Hs
		440348 FYN_HUMAN (7-164): 5.43e-24: 105: 17.50		KAPCA_HUMAN (1345-1709): 1.11e-90: 301: 18.30
+	Hs
		605564 P85A_HUMAN (241-376): 5.42e-23: 102: 19.57		KAPCA_HUMAN (1345-1709): 1.11e-90: 301: 18.30
+	Hs
		136286 P85B_HUMAN (250-376): 7.23e-21: 96.4: 24.03		KAPCA_HUMAN (1345-1709): 1.11e-90: 301: 18.30
+	Mm
		431319 SRC_MOUSE (5-201): 8.43e-15: 77.8: 17.41		KPCE_MOUSE (1352-1719): 4.42e-92: 318: 13.12
+	Hs
		557128 SRC_HUMAN (5-152): 5.68e-12: 68.8: 19.74		AKT1_HUMAN (1362-1695): 4.45e-91: 307: 15.07
+	Mm
		834253 CSK_MOUSE (186-375): 1.4e-33: 131: 26.18		PRAG1_MOUSE (1-91): 5.74e-34: 145: 38.04
+	Hs
		658568 P85A_HUMAN (241-376): 5.42e-23: 102: 19.57		KS6B1_HUMAN (1453-1683): 8.45e-45: 173: 16.17
+	Hs
		943567 GRB2_HUMAN (3-61): 2.31e-17: 82.1: 28.81		HUNK_HUMAN (1405-1659): 1.26e-44: 176: 20.61
+	Hs
		834204 CSK_HUMAN (186-375): 1.98e-33: 131: 26.18		PRAG1_HUMAN (1-91): 6.15e-28: 125: 40.43
+	Hs
		557097 SRC_HUMAN (5-152): 5.68e-12: 68.8: 19.74		KS6B1_HUMAN (1453-1683): 8.45e-45: 173: 16.17
+	Hs
		987722 GRB2_HUMAN (3-61): 2.31e-17: 82.1: 28.81		PEAK3_HUMAN (1653-1743): 1.23e-30: 129: 38.46
+	Hs
		987750 GRB2_HUMAN (3-61): 2.31e-17: 82.1: 28.81		PRAG1_HUMAN (1-91): 6.15e-28: 125: 40.43