HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: PKHA5 (Q9HAU0)
Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)
Gene: PLEKHA5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 1116
+	Hs
		1433514 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		PKHA5_HUMAN (1-1116): 0: 685: 100.00
+	Hs
		988721 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		PKHA5_HUMAN (1-1116): 0: 685: 100.00
+	Hs
		1433516 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		PKHA1_HUMAN (113-359): 3.29e-42: 161: 18.49
+	Hs
		988289 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		ANK2_HUMAN (261-1106): 2.88e-56: 216: 10.80
+	Mm
		988900 RAC1_MOUSE (10-195): 2.03e-80: 239: 63.98		RHG22_MOUSE (131-757): 3.73e-53: 200: 14.33
+	Hs
		1394613 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		ITCH_HUMAN (11-246): 4.77e-29: 127: 16.95
+	Hs
		988324 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		ANK3_HUMAN (378-1098): 3e-50: 197: 11.71
+	Hs
		1015396 RHOG_HUMAN (9-199): 1.71e-77: 231: 54.97		ANK3_HUMAN (378-1098): 3e-50: 197: 11.71
+	Hs
		988484 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		RHG22_HUMAN (139-757): 2.64e-49: 189: 15.64
+	Hs
		132297 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		WWP2_HUMAN (12-206): 8.82e-24: 110: 19.80
+	Hs
		988627 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		MAGI1_HUMAN (1-537): 7.48e-44: 176: 12.32
+	Hs
		601451 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		PKHA1_HUMAN (113-359): 3.29e-42: 161: 18.49
+	Hs
		988724 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		PKHA1_HUMAN (113-359): 3.29e-42: 161: 18.49
+	Hs
		988708 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		PKHA4_HUMAN (142-450): 2.09e-34: 144: 25.94
+	Hs
		601404 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		ITCH_HUMAN (11-246): 4.77e-29: 127: 16.95
+	Hs
		988610 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		ITCH_HUMAN (11-246): 4.77e-29: 127: 16.95
+	Hs
		131717 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		WWP2_HUMAN (12-206): 8.82e-24: 110: 19.80
+	Hs
		131927 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		WWP2_HUMAN (12-206): 8.82e-24: 110: 19.80
+	Hs
		131951 RHOG_HUMAN (9-199): 1.71e-77: 231: 54.97		WWP2_HUMAN (12-206): 8.82e-24: 110: 19.80
+	Sc
		618349 CDC42_YEAST (10-185): 5.83e-85: 251: 66.48		BOI2_YEAST (85-315): 5.68e-10: 65.7: 20.22