Interactor 1: RPA2 (P22138)
DNA-directed RNA polymerase I subunit RPA135 (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (A135) (DNA-directed RNA polymerase I polypeptide 2) (RNA polymerase I subunit 2)
Gene: RPA135

Interactor 2: RPA12 (P32529)
DNA-directed RNA polymerase I subunit RPA12 (A12) (A12.2) (DNA-directed RNA polymerase I 13.7 kDa polypeptide)
Gene: RPA12

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 10393904, 16908835, 11805826, 23209026, 11918799, 16554755, 16429126, 37968396, 24153184
Identification Methods two hybrid, tandem affinity purification, affinity chromatography technology, x-ray crystallography
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpa2_4~TFIIS_C, RNA_POL_M_15KD~RNA_pol_Rpb2_1, RNA_pol_Rpb2_1~TFIIS_C, RNA_pol_Rpb2_6~TFIIS_C
Common GO terms GO:0001054 - RNA polymerase I activity
GO:0005634 - nucleus
GO:0005736 - RNA polymerase I complex
GO:0006360 - transcription by RNA polymerase I
GO:0006361 - transcription initiation at RNA polymerase I promoter
and 4 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1203
Sc

1 125
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Sc
+ Hs
+ Hs
+ Hs
+ Sc

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Last updated: 15 Jul 2024