HitPredict

Interactor 1: PCNA (P17917)
Proliferating cell nuclear antigen (PCNA) (Cyclin) (Mutagen-sensitive 209 protein)
Gene: PCNA

Interactor 2: Q9U9Q1 (Q9U9Q1)
Replication factor C subunit 3 (Activator 1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit)
Gene: RfC38

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DNA_pol3_delta2~PCNA_C, DNA_pol3_delta2~PCNA_N
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006261 - DNA-templated DNA replication GO:0006272 - leading strand elongation
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 260 Dm			1 356
+	Hs
		550904 PCNA_HUMAN (1-259): 9.99e-111: 321: 71.04		RFC3_HUMAN (1-349): 3.06e-103: 309: 60.17
+	Hs
		550888 PCNA_HUMAN (1-259): 9.99e-111: 321: 71.04		RFC4_HUMAN (2-341): 6.83e-99: 298: 25.22
+	Dm
		609501 PCNA_DROME (1-260): 9.6e-112: 323: 100.00		Q9VX15_DROME (2-342): 1.13e-90: 277: 24.93
+	Bt
		1053211 PCNA_BOVIN (1-259): 2.63e-111: 322: 71.04		RFC2_BOVIN (3-341): 5.21e-88: 270: 22.65
+	Bt
		1177677 PCNA_BOVIN (1-259): 2.63e-111: 322: 71.04		Q29RS9_BOVIN (2-341): 1.02e-87: 269: 24.57
+	Hs
		550889 PCNA_HUMAN (1-259): 9.99e-111: 321: 71.04		RFC2_HUMAN (3-341): 6.48e-87: 267: 22.94
+	Hs
		550903 PCNA_HUMAN (1-259): 9.99e-111: 321: 71.04		RFC5_HUMAN (3-339): 6.07e-87: 267: 25.07
+	Dm
		609466 PCNA_DROME (1-260): 9.6e-112: 323: 100.00		Q9VKW3_DROME (3-342): 4.69e-82: 254: 23.91
+	Sc
		586466 PCNA_YEAST (1-259): 8.73e-93: 275: 35.91		RFC2_YEAST (2-342): 4.14e-90: 276: 22.88
+	Sc
		586453 PCNA_YEAST (1-259): 8.73e-93: 275: 35.91		RFC3_YEAST (3-339): 5.32e-82: 255: 24.49
+	Sc
		586451 PCNA_YEAST (1-259): 8.73e-93: 275: 35.91		RFC5_YEAST (1-342): 7.13e-79: 247: 39.77
+	Sc
		586465 PCNA_YEAST (1-259): 8.73e-93: 275: 35.91		RFC4_YEAST (3-346): 1.38e-77: 243: 22.54
+	Hs
		253192 RAD1_HUMAN (2-260): 2.44e-65: 206: 16.18		RFC3_HUMAN (1-349): 3.06e-103: 309: 60.17
+	Hs
		253188 RAD1_HUMAN (2-260): 2.44e-65: 206: 16.18		RFC4_HUMAN (2-341): 6.83e-99: 298: 25.22
+	Hs
		253191 RAD1_HUMAN (2-260): 2.44e-65: 206: 16.18		RFC5_HUMAN (3-339): 6.07e-87: 267: 25.07