HitPredict

Interactor 1: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1

Interactor 2: C5AR1 (P21730)
C5a anaphylatoxin chemotactic receptor 1 (C5a anaphylatoxin chemotactic receptor) (C5a-R) (C5aR) (CD antigen CD88)
Gene: C5AR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.549

Property	Details
Experiments	33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 435 Hs			1 350
+	Hs
		611043 PTN1_HUMAN (1-435): 0: 540: 100.00		CCR6_HUMAN (2-319): 1.65e-78: 246: 24.32
+	Hs
		611012 PTN1_HUMAN (1-435): 0: 540: 100.00		APJ_HUMAN (18-343): 5.09e-67: 217: 24.71
+	Hs
		611399 PTN1_HUMAN (1-435): 0: 540: 100.00		C5AR2_HUMAN (2-339): 6.1e-65: 210: 38.71
+	Hs
		607557 PTN2_HUMAN (3-435): 1.98e-156: 450: 52.98		CCR6_HUMAN (2-319): 1.65e-78: 246: 24.32
+	Hs
		607639 PTN2_HUMAN (3-435): 1.98e-156: 450: 52.98		CML1_HUMAN (3-348): 5.86e-78: 245: 32.51
+	Hs
		607666 PTN2_HUMAN (3-435): 1.98e-156: 450: 52.98		C5AR2_HUMAN (2-339): 6.1e-65: 210: 38.71
+	Hs
		611145 PTN1_HUMAN (1-435): 0: 540: 100.00		C3AR_HUMAN (201-339): 1.12e-18: 88.6: 35.71
+	Hs
		221445 PTPRD_HUMAN (1-278): 4.82e-109: 355: 31.45		OX2R_HUMAN (2-348): 1.11e-65: 215: 15.37
+	Hs
		607593 PTN2_HUMAN (3-435): 1.98e-156: 450: 52.98		C3AR_HUMAN (201-339): 1.12e-18: 88.6: 35.71
+	Hs
		471738 PTPRC_HUMAN (16-337): 2e-77: 263: 22.95		CXCR4_HUMAN (6-323): 5.7e-66: 213: 25.93
+	Hs
		835472 PTN9_HUMAN (20-279): 3.37e-52: 186: 39.21		CCR2_HUMAN (26-325): 3.47e-66: 215: 22.55
+	Hs
		849045 PTN9_HUMAN (20-279): 3.37e-52: 186: 39.21		C5AR2_HUMAN (2-339): 6.1e-65: 210: 38.71
+	Hs
		956853 PTN11_HUMAN (39-274): 7.82e-49: 177: 38.80		CXCR4_HUMAN (6-323): 5.7e-66: 213: 25.93
+	Hs
		726290 PTN18_HUMAN (342-434): 2.52e-17: 85.8: 12.87		SSR4_HUMAN (38-320): 4.59e-67: 217: 28.43
+	Hs
		711037 PTN6_HUMAN (342-432): 1.7e-12: 71.2: 10.48		SSR2_HUMAN (2-347): 1.52e-69: 223: 25.98
+	Hs
		711073 PTN6_HUMAN (342-432): 1.7e-12: 71.2: 10.48		CXCR4_HUMAN (6-323): 5.7e-66: 213: 25.93