HitPredict

Interactor 1: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1

Interactor 2: CCR6 (P51684)
C-C chemokine receptor type 6 (C-C CKR-6) (CC-CKR-6) (CCR-6) (Chemokine receptor-like 3) (CKR-L3) (DRY6) (G-protein coupled receptor 29) (GPR-CY4) (GPRCY4) (LARC receptor) (CD antigen CD196)
Gene: CCR6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 435 Hs			1 374
+	Hs
		611031 PTN1_HUMAN (1-435): 0: 540: 100.00		CXCR3_HUMAN (7-340): 1.98e-80: 252: 36.72
+	Hs
		611012 PTN1_HUMAN (1-435): 0: 540: 100.00		APJ_HUMAN (23-359): 1.1e-69: 225: 23.08
+	Hs
		607557 PTN2_HUMAN (3-435): 1.98e-156: 450: 52.98		CCR6_HUMAN (1-374): 3.18e-94: 287: 100.00
+	Hs
		141816 PTN1_HUMAN (1-435): 0: 540: 100.00		ACKR2_HUMAN (21-331): 1.94e-49: 172: 35.76
+	Hs
		141815 PTN2_HUMAN (3-435): 1.98e-156: 450: 52.98		ACKR2_HUMAN (21-331): 1.94e-49: 172: 35.76
+	Hs
		221445 PTPRD_HUMAN (1-278): 4.82e-109: 355: 31.45		OX2R_HUMAN (7-373): 2.5e-72: 234: 17.63
+	Hs
		471738 PTPRC_HUMAN (16-337): 2e-77: 263: 22.95		CXCR4_HUMAN (14-339): 2.45e-71: 228: 32.11
+	Hs
		658862 PTPRD_HUMAN (1-278): 4.82e-109: 355: 31.45		LPAR6_HUMAN (53-370): 7.56e-36: 135: 29.88
+	Hs
		669317 PTPRS_HUMAN (1-278): 2.04e-109: 356: 30.74		ACKR3_HUMAN (53-329): 3.36e-33: 128: 29.64
+	Hs
		658848 PTPRD_HUMAN (1-278): 4.82e-109: 355: 31.45		ACKR3_HUMAN (53-329): 3.36e-33: 128: 29.64
+	Hs
		522595 PTPRF_HUMAN (19-278): 1.61e-105: 345: 30.94		ACKR3_HUMAN (53-329): 3.36e-33: 128: 29.64
+	Hs
		835472 PTN9_HUMAN (20-279): 3.37e-52: 186: 39.21		CCR2_HUMAN (35-359): 3.34e-72: 231: 33.13
+	Hs
		956853 PTN11_HUMAN (39-274): 7.82e-49: 177: 38.80		CXCR4_HUMAN (14-339): 2.45e-71: 228: 32.11
+	Hs
		726290 PTN18_HUMAN (342-434): 2.52e-17: 85.8: 12.87		SSR4_HUMAN (37-336): 1.68e-73: 235: 26.62
+	Hs
		711037 PTN6_HUMAN (342-432): 1.7e-12: 71.2: 10.48		SSR2_HUMAN (1-366): 5.19e-74: 235: 26.06
+	Hs
		711073 PTN6_HUMAN (342-432): 1.7e-12: 71.2: 10.48		CXCR4_HUMAN (14-339): 2.45e-71: 228: 32.11