Interactor 1: SHIP1 (P97573)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (EC 3.1.3.86) (Inositol polyphosphate-5-phosphatase D) (EC 3.1.3.56) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (EC 3.1.3.36) (SH2 domain-containing inositol 5'-phosphatase 1) (SH2 domain-containing inositol phosphatase 1) (SHIP-1)
Gene: Inpp5d

Interactor 2: FCGR2 (Q63203)
Low affinity immunoglobulin gamma Fc region receptor II (Fc-gamma RII) (FcRII) (IgG Fc receptor II beta) (CD antigen CD32)
Gene: FCGR2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 11970986
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0016064 - immunoglobulin mediated immune response
GO:0030889 - negative regulation of B cell proliferation
GO:0050777 - negative regulation of immune response
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1190
Rn

1 285
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024