HitPredict

Interactor 1: COF1 (P23528)
Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)
Gene: CFL1

Interactor 2: MY18A (Q92614)
Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210)
Gene: MYO18A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane GO:0043066 - negative regulation of apoptotic process GO:0051015 - actin filament binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 166 Hs			1 2054
+	Hs
		1268120 COF2_HUMAN (1-166): 1.68e-71: 214: 80.72		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		894675 DEST_HUMAN (1-166): 3.71e-69: 208: 71.08		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		1016503 TWF1_HUMAN (3-157): 1.01e-34: 126: 21.52		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		618006 COF1_HUMAN (1-166): 4.46e-72: 215: 100.00		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		725077 COF2_HUMAN (1-166): 1.68e-71: 214: 80.72		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		724739 DEST_HUMAN (1-166): 3.71e-69: 208: 71.08		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		724797 TWF1_HUMAN (3-157): 1.01e-34: 126: 21.52		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		724875 TWF2_HUMAN (3-151): 2.29e-29: 111: 17.11		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96