HitPredict

Interactor 1: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Interactor 2: AMER1 (Q5JTC6)
APC membrane recruitment protein 1 (Amer1) (Protein FAM123B) (Wilms tumor gene on the X chromosome protein)
Gene: AMER1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

The method score is based on:

Property	Details
Experiments	26496610, 17510365, 24251807
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008013 - beta-catenin binding GO:0016055 - Wnt signaling pathway GO:0045732 - positive regulation of protein catabolic process and 1 others more... GO:0090090 - negative regulation of canonical Wnt signaling pathway
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	2843
Hs

1	1135

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024