HitPredict

Interactor 1: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Interactor 2: SYNCI (Q9H7C4)
Syncoilin (Syncoilin intermediate filament 1) (Syncoilin-1)
Gene: SYNC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2843 Hs			1 482
+	Hs
		531535 APC_HUMAN (1-2843): 0: 1316: 100.00		K2C5_HUMAN (133-473): 1.55e-63: 218: 16.71
+	Hs
		280854 APC_HUMAN (1-2843): 0: 1316: 100.00		KRT37_HUMAN (167-476): 9.33e-57: 196: 17.49
+	Hs
		443883 SRRM2_HUMAN (943-2827): 1.37e-30: 135: 8.96		VIME_HUMAN (154-456): 2.16e-104: 321: 21.70
+	Hs
		443743 CIC_HUMAN (722-2643): 2.1e-17: 92.4: 7.79		VIME_HUMAN (154-456): 2.16e-104: 321: 21.70
+	Hs
		1205250 CIC_HUMAN (722-2643): 2.1e-17: 92.4: 7.79		K2C73_HUMAN (133-468): 3.32e-82: 265: 16.67