HitPredict

Interactor 1: WIPF3 (A6NGB9)
WAS/WASL-interacting protein family member 3 (Corticosteroids and regional expression protein 16 homolog)
Gene: WIPF3

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 483 Hs			1 375
+	Hs
		554315 MUC1_HUMAN (83-478): 1.47e-17: 88: 12.78		ACTBL_HUMAN (2-375): 0: 735: 91.71
+	Hs
		1122431 SRCAP_HUMAN (1-467): 1.67e-09: 62.6: 13.89		ACTBL_HUMAN (2-375): 0: 735: 91.71
+	Hs
		891686 MAP1A_HUMAN (3-454): 1.32e-21: 101: 13.27		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		62644 WIPF3_HUMAN (33-483): 2.9e-22: 101: 100.00		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		891920 WIPF2_HUMAN (31-460): 3.17e-21: 98: 27.35		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		929941 WIPF2_HUMAN (31-460): 3.17e-21: 98: 27.35		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		62645 WIPF3_HUMAN (33-483): 2.9e-22: 101: 100.00		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		932278 WIPF2_HUMAN (31-460): 3.17e-21: 98: 27.35		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		554290 MUC1_HUMAN (83-478): 1.47e-17: 88: 12.78		ACTA_HUMAN (2-375): 0: 591: 94.12
+	Hs
		891853 SRCAP_HUMAN (1-467): 1.67e-09: 62.6: 13.89		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		929905 SRCAP_HUMAN (1-467): 1.67e-09: 62.6: 13.89		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		932156 MDC1_HUMAN (25-481): 1.07e-11: 69.5: 10.70		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		203220 SYNJ1_HUMAN (81-468): 1.1e-10: 66.4: 12.53		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Dm
		501445 CPN_DROME (1-437): 9.51e-09: 59.9: 10.61		ACT5_DROME (2-375): 0: 596: 95.99
+	Hs
		932219 SRCAP_HUMAN (1-467): 1.67e-09: 62.6: 13.89		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		932341 CIC_HUMAN (7-480): 6.61e-09: 60.6: 10.74		ACTC_HUMAN (2-375): 0: 592: 94.12