HitPredict

Interactor 1: PO5F1 (P20263)
POU domain, class 5, transcription factor 1 (NF-A3) (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3)
Gene: Pou5f1

Interactor 2: HELLS (Q60848)
Lymphocyte-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein)
Gene: HELLS

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	20362541, 20362542, 22083510
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:1990830 - cellular response to leukemia inhibitory factor
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 352 Mm			1 821
+	Mm
		73004 PO5F1_MOUSE (1-352): 1.24e-99: 300: 100.00		B1AR17_MOUSE (34-811): 0: 587: 23.17
+	Mm
		629322 PO5F1_MOUSE (1-352): 1.24e-99: 300: 100.00		CHD4_MOUSE (34-811): 0: 577: 22.87
+	Mm
		59098 PO5F1_MOUSE (1-352): 1.24e-99: 300: 100.00		CHD5_MOUSE (34-818): 7.75e-180: 567: 23.10
+	Mm
		629255 PO5F1_MOUSE (1-352): 1.24e-99: 300: 100.00		SMCA4_MOUSE (1-820): 0: 567: 25.26
+	Mm
		629309 PO5F1_MOUSE (1-352): 1.24e-99: 300: 100.00		SMCA2_MOUSE (1-820): 0: 566: 25.31
+	Hs
		895803 LHX2_HUMAN (202-351): 2.79e-34: 131: 24.53		HELLS_HUMAN (1-821): 0: 722: 91.12
+	Hs
		1033801 PO5F1_HUMAN (1-352): 3.02e-89: 274: 82.50		CHD7_HUMAN (3-805): 5.73e-180: 576: 23.62
+	Mm
		629413 PO5F1_MOUSE (1-352): 1.24e-99: 300: 100.00		SMCA5_MOUSE (86-817): 1.16e-171: 525: 28.49
+	Hs
		1088400 HMBX1_HUMAN (45-323): 2.92e-40: 148: 17.23		CHD3_HUMAN (34-811): 0: 589: 23.17
+	Hs
		895809 LHX2_HUMAN (202-351): 2.79e-34: 131: 24.53		CHD7_HUMAN (3-805): 5.73e-180: 576: 23.62
+	Hs
		895693 LHX2_HUMAN (202-351): 2.79e-34: 131: 24.53		SMCA4_HUMAN (1-820): 0: 568: 24.56
+	Hs
		877571 LHX1_HUMAN (202-349): 1.48e-29: 119: 23.12		CHD7_HUMAN (3-805): 5.73e-180: 576: 23.62
+	Hs
		895692 LHX2_HUMAN (202-351): 2.79e-34: 131: 24.53		SMCA2_HUMAN (1-820): 0: 564: 25.31
+	Hs
		877505 LHX1_HUMAN (202-349): 1.48e-29: 119: 23.12		SMCA2_HUMAN (1-820): 0: 564: 25.31
+	Hs
		1088425 ZFHX4_HUMAN (2-280): 2.72e-12: 70.4: 17.01		CHD3_HUMAN (34-811): 0: 589: 23.17
+	Hs
		703283 LHX2_HUMAN (202-351): 2.79e-34: 131: 24.53		SMCA1_HUMAN (90-812): 1.58e-171: 524: 28.85
+	Hs
		1132796 ZFHX4_HUMAN (2-280): 2.72e-12: 70.4: 17.01		CHD4_HUMAN (34-811): 0: 577: 22.87