HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: CD226 (Q15762)
CD226 antigen (DNAX accessory molecule 1) (DNAM-1) (CD antigen CD226)
Gene: CD226

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 218 Hs			1 336
+	Hs
		956243 RAB2A_HUMAN (10-197): 4.01e-95: 278: 56.92		CXAR_HUMAN (1-335): 1.74e-47: 165: 15.56
+	Hs
		956432 RAB2A_HUMAN (10-197): 4.01e-95: 278: 56.92		NECT2_HUMAN (20-189): 7.04e-39: 146: 17.17
+	Hs
		956560 RAB2A_HUMAN (10-197): 4.01e-95: 278: 56.92		JAM1_HUMAN (1-294): 1.14e-40: 145: 18.18
+	Hs
		630762 RAB4A_HUMAN (1-218): 3.71e-86: 255: 100.00		CXAR_HUMAN (1-335): 1.74e-47: 165: 15.56
+	Hs
		956467 RAB2A_HUMAN (10-197): 4.01e-95: 278: 56.92		JAM3_HUMAN (23-315): 1.46e-37: 138: 17.63
+	Hs
		976195 RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33		CXAR_HUMAN (1-335): 1.74e-47: 165: 15.56
+	Hs
		630919 RAB4A_HUMAN (1-218): 3.71e-86: 255: 100.00		NECT2_HUMAN (20-189): 7.04e-39: 146: 17.17
+	Hs
		976586 RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33		NECT3_HUMAN (8-203): 1.97e-41: 153: 20.10
+	Hs
		516664 RB11B_HUMAN (3-217): 4.38e-83: 247: 43.26		VSIG8_HUMAN (8-273): 3.44e-40: 147: 15.17
+	Hs
		976465 RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33		NECT2_HUMAN (20-189): 7.04e-39: 146: 17.17
+	Hs
		976620 RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33		PD1L1_HUMAN (1-287): 9.87e-40: 143: 18.24
+	Mm
		981421 RAB1A_MOUSE (3-218): 1.74e-85: 253: 38.43		PD1L1_MOUSE (1-294): 3.66e-37: 136: 16.89
+	Mm
		1362180 RAB14_MOUSE (3-217): 2.22e-83: 248: 57.21		PD1L1_MOUSE (1-294): 3.66e-37: 136: 16.89
+	Mm
		857894 RB11B_MOUSE (3-217): 7.99e-83: 247: 43.26		PD1L1_MOUSE (1-294): 3.66e-37: 136: 16.89
+	Hs
		630932 RAB4A_HUMAN (1-218): 3.71e-86: 255: 100.00		LRIG1_HUMAN (13-325): 3.43e-30: 123: 12.54
+	Hs
		541331 RAB4A_HUMAN (1-218): 3.71e-86: 255: 100.00		FGFR1_HUMAN (27-333): 8.9e-14: 74.3: 11.40
+	Hs
		541423 RAB1A_HUMAN (3-218): 1.74e-85: 253: 38.43		FGFR1_HUMAN (27-333): 8.9e-14: 74.3: 11.40
+	Hs
		541422 RAB14_HUMAN (3-217): 2.22e-83: 248: 57.21		FGFR1_HUMAN (27-333): 8.9e-14: 74.3: 11.40
+	Hs
		541510 RB11B_HUMAN (3-217): 4.38e-83: 247: 43.26		FGFR1_HUMAN (27-333): 8.9e-14: 74.3: 11.40
+	Hs
		976711 RB11A_HUMAN (3-217): 3.63e-83: 247: 42.33		ROBO1_HUMAN (2-231): 6.46e-10: 62.7: 13.36