Interactor 1: NOT1 (P25655)
General negative regulator of transcription subunit 1 (Cell division cycle protein 39)
Gene: CDC39

Interactor 2: NOT5 (Q12514)
General negative regulator of transcription subunit 5
Gene: NOT5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 9511744, 12215531, 24121231, 19707589, 11023781, 16263706, 30948432, 18467557, 35357307, 37968396, 20386698, 22615397, 21669201, 25914052
Identification Methods two hybrid, coimmunoprecipitation, pull down, affinity chromatography technology, biochemical, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains NOT2_3_5~Not1
Common GO terms GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006368 - transcription elongation by RNA polymerase II
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 2108
Sc

1 560
+ Sc
+ Mm
+ Hs
+ Dm

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Last updated: 15 Jul 2024