Interactor 1: KAP0 (P10644)
cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue-specific extinguisher 1) (TSE1)
Gene: PRKAR1A
Interactor 2: KAPCB (P22694)
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)
Gene: PRKACB
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.976 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 31980649, 28514442, 33961781, 32707033, 36736316, 40437099, 23455922, unassigned2173, 21880142, unassigned3799 |
| Identification Methods | affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down, two hybrid, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~cNMP_binding, Pkinase~RIIa |
| Common GO terms | GO:0005813 - centrosome GO:0005829 - cytosol GO:0005952 - cAMP-dependent protein kinase complex GO:0031625 - ubiquitin protein ligase binding GO:0097546 - ciliary base |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
