HitPredict

Interactor 1: PSA7 (P21242)
Probable proteasome subunit alpha type-7 (Macropain subunit C1) (Multicatalytic endopeptidase complex subunit C1) (Proteasome component C1) (Proteinase YSCE subunit 1)
Gene: PRE10

Interactor 2: PSA1 (P21243)
Proteasome subunit alpha type-1 (Macropain subunit C7-alpha) (Multicatalytic endopeptidase complex C7) (Proteasome component C7-alpha) (Proteasome component Y8) (Proteinase YSCE subunit 7) (SCL1 suppressor protein)
Gene: SCL1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 10688190, 11595789, 11805826, 16429126, 31848235, 22940862, 26245374, 16554755, 18467557, 37968396, 15253422, 22615397
Identification Methods two hybrid, tandem affinity purification, affinity chromatography technology, cross-linking study, protein complementation assay, dihydrofolate reductase reconstruction, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome, Proteasome~Proteasome_A_N, Proteasome_A_N~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0019773 - proteasome core complex, alpha-subunit complex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 288
Sc

1 252
+ Sp
+ Dm
+ Dm
+ Hs
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025