Protein: PSA7
Probable proteasome subunit alpha type-7 (Macropain subunit C1) (Multicatalytic endopeptidase complex subunit C1) (Proteasome component C1) (Proteinase YSCE subunit 1)

Gene: PSA7, PRE10
Organism: Saccharomyces cerevisiae S288C
Interactions: 100
UniProt ID: P21242

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0019773 - proteasome core complex, alpha-subunit complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636533

PSB4
Proteasome subunit beta type-4

19

20

Small-scale

0.987

High

636532

PSA1
Proteasome subunit alpha type-1

12

19

Small-scale

0.979

High

636587

PSA6
Proteasome subunit alpha type-6

9

20

Small-scale

0.970

High

636553

PSA5
Proteasome subunit alpha type-5

8

20

Small-scale

0.967

High

636539

PSA3
Proteasome subunit alpha type-3

7

19

Small-scale

0.963

High

636550

PSB5
Proteasome subunit beta type-5

8

20

Small-scale

0.963

High

636551

PSB7
Proteasome subunit beta type-7

7

20

Small-scale

0.958

High

636540

PSA2
Proteasome subunit alpha type-2

7

20

Small-scale

0.955

High

636588

PSA4
Proteasome subunit alpha type-4

6

20

Small-scale

0.943

High

636570

PSB1
Proteasome subunit beta type-1

5

20

Small-scale

0.919

High

636541

PSB6
Proteasome subunit beta type-6

4

20

High-throughput

0.892

High

636567

UMP1
Proteasome maturation factor UMP1

4

1

Small-scale

0.881

High

636545

PSB3
Proteasome subunit beta type-3

3

20

High-throughput

0.847

High

636593

BLM10
Proteasome activator BLM10

3

8

Small-scale

0.840

High

636542

PSB2
Proteasome subunit beta type-2

3

20

Small-scale

0.839

High

636558

PRS6A
26S proteasome regulatory subunit 6A

3

20

High-throughput

0.827

High

636618

RPN5
26S proteasome regulatory subunit RPN5

3

20

Small-scale

0.827

High

636594

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

18

20

Small-scale

0.762

High

636531

PSA7
Probable proteasome subunit alpha type-7

2

19

High-throughput

0.754

High

636560

PRS7
26S proteasome regulatory subunit 7 homolog

2

20

Small-scale

0.754

High

636598

PRS10
26S proteasome subunit RPT4

2

20

High-throughput

0.754

High

636619

RPN6
26S proteasome regulatory subunit RPN6

2

20

Small-scale

0.754

High

636573

RPN1
26S proteasome regulatory subunit RPN1

4

20

Small-scale

0.672

High

636617

POC4
Proteasome chaperone 4

1

1

Small-scale

0.665

High

636548

CDC48
Cell division control protein 48

1

15

High-throughput

0.618

High

636559

PRS6B
26S proteasome regulatory subunit 6B homolog

1

20

High-throughput

0.618

High

636564

POC2
Proteasome assembly chaperone 2

1

1

High-throughput

0.618

High

636589

PRS4
26S proteasome regulatory subunit 4 homolog

1

20

High-throughput

0.618

High

636603

PRS8
26S proteasome regulatory subunit 8 homolog

1

20

High-throughput

0.618

High

636585

RPN3
26S proteasome regulatory subunit RPN3

2

8

High-throughput

0.611

High

636534

DBF2
Cell cycle protein kinase DBF2

2

1

Small-scale

0.602

High

636543

SIS1
Protein SIS1

2

7

High-throughput

0.601

High

636555

RPN2
26S proteasome regulatory subunit RPN2

2

20

Small-scale

0.595

High

636552

IMB3
Importin subunit beta-3

2

1

High-throughput

0.588

High

636554

RPN12
26S proteasome regulatory subunit RPN12

2

7

Small-scale

0.586

High

636572

ECM29
Proteasome component ECM29

2

13

High-throughput

0.584

High

636607

RPN9
26S proteasome regulatory subunit RPN9

2

14

High-throughput

0.584

High

636615

RPN8
26S proteasome regulatory subunit RPN8

2

20

Small-scale

0.584

High

636556

SUI1
Eukaryotic translation initiation factor eIF-1

2

4

Small-scale

0.555

High

636547

FUB1
Silencing boundary-establishment protein FUB1

1

1

High-throughput

0.553

High

636608

POC1
Proteasome chaperone 1

1

1

High-throughput

0.553

High

636601

ZDS2
Protein ZDS2

2

1

High-throughput

0.537

High

636586

SSB2
Ribosome-associated molecular chaperone SSB2

1

12

High-throughput

0.536

High

636538

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

1

High-throughput

0.515

High

602314

PHO85
Cyclin-dependent protein kinase PHO85

1

7

High-throughput

0.501

High

636536

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

3

High-throughput

0.501

High

636561

NOT4
General negative regulator of transcription subunit 4

1

3

High-throughput

0.501

High

636569

RCK1
Serine/threonine-protein kinase RCK1

1

3

High-throughput

0.501

High

636571

KSP1
Serine/threonine-protein kinase KSP1

1

3

High-throughput

0.501

High

636583

RSP5
E3 ubiquitin-protein ligase RSP5

1

12

High-throughput

0.501

High

636596

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

5

High-throughput

0.501

High

636580

DHE5
NADP-specific glutamate dehydrogenase 2

1

0

High-throughput

0.493

High

636581

RV167
Reduced viability upon starvation protein 167

1

2

High-throughput

0.489

High

636591

COPB2
Coatomer subunit beta'

1

3

High-throughput

0.489

High

636592

GNA1
Glucosamine 6-phosphate N-acetyltransferase

1

0

High-throughput

0.486

High

636537

KC12
Casein kinase I homolog 2

1

0

High-throughput

0.480

High

150257

RPN13
26S proteasome regulatory subunit RPN13

1

1

High-throughput

0.479

High

584885

TRM1
tRNA

1

1

High-throughput

0.479

High

599323

FUS3
Mitogen-activated protein kinase FUS3

1

4

High-throughput

0.479

High

603003

EST1
Telomere elongation protein EST1

1

1

High-throughput

0.479

High

636535

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.479

High

636549

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

636563

CENPA
Histone H3-like centromeric protein CSE4

1

2

High-throughput

0.479

High

636576

RPN10
26S proteasome regulatory subunit RPN10

1

12

High-throughput

0.479

High

636578

DHH1
ATP-dependent RNA helicase DHH1

1

3

High-throughput

0.479

High

636582

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

2

High-throughput

0.479

High

636595

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

13

High-throughput

0.479

High

636600

APJ1
J domain-containing protein APJ1

1

7

High-throughput

0.479

High

636602

H3
Histone H3

1

2

High-throughput

0.479

High

636604

TOM1
E3 ubiquitin-protein ligase TOM1

1

13

High-throughput

0.479

High

636606

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.479

High

636620

CMR1
DNA damage-binding protein CMR1

1

3

High-throughput

0.479

High

381867

H4
Histone H4

1

0

High-throughput

0.458

High

506233

HAP1
Heme-responsive zinc finger transcription factor HAP1

1

0

High-throughput

0.458

High

633231

CKS1
Cyclin-dependent kinases regulatory subunit

1

0

Small-scale

0.458

High

636544

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

636568

HSM3
DNA mismatch repair protein HSM3

1

0

Small-scale

0.458

High

636610

KYNU
Kynureninase

1

0

High-throughput

0.458

High

636611

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

636614

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.458

High

636616

YP150
Putative serine/threonine-protein kinase YPL150W

1

1

High-throughput

0.457

High

523042

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

636546

MAS5
Mitochondrial protein import protein MAS5

1

7

High-throughput

0.445

High

636574

SSZ1
Ribosome-associated complex subunit SSZ1

1

11

High-throughput

0.445

High

636557

YPT7
Ypt/Rab-type GTPase YPT7

1

2

Small-scale

0.437

High

636565

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

636566

ATG8
Autophagy-related protein 8

1

5

High-throughput

0.437

High

636577

TEM1
Protein TEM1

1

2

High-throughput

0.437

High

636609

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.437

High

636612

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

636562

AP1S1
AP-1 complex subunit sigma-1

1

0

High-throughput

0.426

High

636597

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

636605

RIM13
Calpain-like protease 1

2

0

Small-scale

0.317

High

636613

YL076
Putative uncharacterized protein YLR076C

2

0

Small-scale

0.304

High

636575

NVJ1
Nucleus-vacuole junction protein 1

1

0

High-throughput

0.249

Low

636579

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

636590

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.249

Low

636584

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.232

Low

636599

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025