HitPredict

Interactor 1: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Interactor 2: MCM5 (P33992)
DNA replication licensing factor MCM5 (EC 3.6.4.12) (CDC46 homolog) (P1-CDC46)
Gene: MCM5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	32912968, 14743216
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 734
+	Hs
		639681 IKBA_HUMAN (1-317): 2.59e-84: 258: 100.00		MCM7_HUMAN (27-730): 0: 649: 27.57
+	Hs
		832413 ANK3_HUMAN (1-130): 1.86e-30: 123: 10.77		MCM2_HUMAN (28-732): 0: 675: 30.09
+	Hs
		708430 ANK3_HUMAN (1-130): 1.86e-30: 123: 10.77		MCM4_HUMAN (6-724): 0: 672: 30.20
+	Hs
		1021402 ANK3_HUMAN (1-130): 1.86e-30: 123: 10.77		MCM6_HUMAN (12-705): 0: 642: 27.41
+	Hs
		708966 MIB1_HUMAN (187-313): 7.22e-23: 101: 18.11		MCM7_HUMAN (27-730): 0: 649: 27.57
+	Hs
		587443 NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35		MCM7_HUMAN (27-730): 0: 649: 27.57