HitPredict

Interactor 1: HMGB2 (P26583)
High mobility group protein B2 (High mobility group protein 2) (HMG-2)
Gene: HMGB2

Interactor 2: H2B1H (Q93079)
Histone H2B type 1-H (H2B-clustered histone 9) (Histone H2B.j) (H2B/j)
Gene: H2BC9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 209 Hs			1 126
+	Hs
		449786 HMGB1_HUMAN (1-174): 3.53e-42: 143: 86.21		H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00
+	Hs
		643248 HMGB2_HUMAN (1-187): 3.05e-41: 140: 100.00		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		643302 HMGB2_HUMAN (1-187): 3.05e-41: 140: 100.00		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		175767 HMGB3_HUMAN (13-176): 1.26e-39: 136: 70.73		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		297497 TOX4_HUMAN (91-170): 1.08e-31: 122: 33.75		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		886084 TFAM_HUMAN (9-190): 7.47e-31: 114: 21.68		H2B1D_HUMAN (1-126): 3.03e-54: 167: 98.41
+	Hs
		1087421 HM20A_HUMAN (64-203): 2.16e-17: 81: 22.92		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		707756 HM20A_HUMAN (64-203): 2.16e-17: 81: 22.92		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		918706 HM20A_HUMAN (64-203): 2.16e-17: 81: 22.92		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Ce
		136643 SSP1B_CAEEL (91-196): 3.14e-20: 89.8: 31.13		H2B1_CAEEL (8-126): 8.57e-50: 156: 80.67
+	Ce
		136714 SSP1B_CAEEL (91-196): 3.14e-20: 89.8: 31.13		H2B4_CAEEL (22-126): 8.35e-49: 153: 87.62
+	Hs
		241615 CIC_HUMAN (3-100): 1.66e-11: 64.7: 22.45		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		1282968 HM20A_HUMAN (64-203): 2.16e-17: 81: 22.92		H2B1A_HUMAN (1-126): 1.15e-47: 151: 84.25
+	Sc
		355755 NHP6A_YEAST (75-164): 2.99e-25: 96: 44.44		H2B2_YEAST (3-125): 4.15e-41: 134: 71.55
+	Sc
		355756 NHP6B_YEAST (73-164): 5.93e-24: 92.9: 42.39		H2B2_YEAST (3-125): 4.15e-41: 134: 71.55
+	Hs
		420830 SSRP1_HUMAN (5-84): 2.82e-09: 57.9: 35.00		H2B1J_HUMAN (1-126): 7.3e-55: 169: 97.62
+	Hs
		567668 UBF1_HUMAN (10-158): 1.47e-09: 58.9: 24.72		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Sc
		355313 NHP6A_YEAST (75-164): 2.99e-25: 96: 44.44		H2B1_YEAST (4-125): 8.17e-37: 123: 72.13
+	Sc
		355314 NHP6B_YEAST (73-164): 5.93e-24: 92.9: 42.39		H2B1_YEAST (4-125): 8.17e-37: 123: 72.13
+	Sc
		355430 IXR1_YEAST (79-209): 2.58e-16: 78.6: 21.37		H2B1_YEAST (4-125): 8.17e-37: 123: 72.13