HitPredict

Interactor 1: PSB4 (P22141)
Proteasome subunit beta type-4 (Macropain subunit C11) (Multicatalytic endopeptidase complex subunit C11) (Proteasome component C11) (Proteinase YSCE subunit 11)
Gene: PRE1

Interactor 2: PSA3 (P23638)
Proteasome subunit alpha type-3 (Macropain subunit Y13) (Multicatalytic endopeptidase complex subunit Y13) (Proteasome component Y13) (Proteinase YSCE subunit 13)
Gene: PRE9

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 11029046, 11805837, 37968396, 15242647, 16554755, 28322792, 12409293, 18435761, 37653242, 31848235, 15917626, 21321079, 21878652, 22940862, 17431397
Identification Methods coimmunoprecipitation, anti tag coimmunoprecipitation, affinity chromatography technology, biochemical, cross-linking study, pull down, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 198
Sc

1 258
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Last updated: 11Aug2025