HitPredict

Interactor 1: PANC (P31663)
Pantothenate synthetase (PS) (EC 6.3.2.1) (Pantoate--beta-alanine ligase) (Pantoate-activating enzyme)
Gene: PANC

Interactor 2: PANC (P31663)
Pantothenate synthetase (PS) (EC 6.3.2.1) (Pantoate--beta-alanine ligase) (Pantoate-activating enzyme)
Gene: PANC

Species: Escherichia coli K-12

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	20059543, 16858726, 24627523
Identification Methods	x-ray crystallography, nuclear magnetic resonance, blue native page, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Pantoate_ligase~Pantoate_ligase
Common GO terms	GO:0004592 - pantoate-beta-alanine ligase activity GO:0005524 - ATP binding GO:0005829 - cytosol GO:0015940 - pantothenate biosynthetic process GO:0042803 - protein homodimerization activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 283 Ec			1 283
+	Sp
		999710 PANC_SCHPO (1-278): 1.55e-150: 424: 59.35		PANC_SCHPO (1-278): 1.55e-150: 424: 59.35
+	Cj
		1351192 PANC_CAMJE (1-281): 1.75e-142: 403: 40.07		PANC_CAMJE (1-281): 1.75e-142: 403: 40.07
+	Hp
		879630 PANC_HELPY (1-280): 1.77e-125: 360: 40.70		PANC_HELPY (1-280): 1.77e-125: 360: 40.70
+	Sc
		774042 PANC_YEAST (1-280): 2.92e-124: 358: 37.42		PANC_YEAST (1-280): 2.92e-124: 358: 37.42