HitPredict

Interactor 1: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Interactor 2: ASAP1 (Q9ULH1)
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)
Gene: ASAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~I-set, PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH3_9
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 802 Hs			1 1129
+	Hs
		541752 FGFR1_HUMAN (3-794): 0: 714: 54.76		ASAP1_HUMAN (17-1129): 0: 826: 100.00
+	Hs
		207902 NTRK1_HUMAN (135-751): 2.17e-160: 487: 26.53		ASAP2_HUMAN (21-967): 0: 644: 55.31
+	Hs
		648594 FGFR4_HUMAN (13-802): 0: 755: 100.00		DP13B_HUMAN (45-453): 5.6e-98: 327: 16.03
+	Hs
		648727 FGFR4_HUMAN (13-802): 0: 755: 100.00		DP13A_HUMAN (45-456): 7.83e-92: 312: 16.39
+	Hs
		541751 FGFR1_HUMAN (3-794): 0: 714: 54.76		DP13A_HUMAN (45-456): 7.83e-92: 312: 16.39
+	Hs
		650367 FGFR3_HUMAN (5-799): 0: 720: 61.07		ARAP1_HUMAN (368-620): 3.84e-58: 222: 24.90
+	Hs
		931912 EPHA5_HUMAN (4-771): 0: 615: 18.43		DP13A_HUMAN (45-456): 7.83e-92: 312: 16.39
+	Hs
		1147462 EPHA7_HUMAN (4-781): 0: 605: 19.78		DP13A_HUMAN (45-456): 7.83e-92: 312: 16.39
+	Hs
		710371 EPHA2_HUMAN (4-789): 0: 587: 19.52		DP13B_HUMAN (45-453): 5.6e-98: 327: 16.03
+	Hs
		710557 EPHA2_HUMAN (4-789): 0: 587: 19.52		DP13A_HUMAN (45-456): 7.83e-92: 312: 16.39
+	Hs
		648605 FGFR4_HUMAN (13-802): 0: 755: 100.00		SMAP2_HUMAN (436-549): 5.12e-16: 84: 36.21
+	Hs
		1147465 EPHA7_HUMAN (4-781): 0: 605: 19.78		AGAP1_HUMAN (361-662): 3.34e-62: 230: 28.30
+	Hs
		641221 FGFR2_HUMAN (4-797): 0: 748: 56.44		SMAP2_HUMAN (436-549): 5.12e-16: 84: 36.21
+	Hs
		95982 EPHA7_HUMAN (4-781): 0: 605: 19.78		E7EUN2_HUMAN (361-662): 4.86e-60: 226: 28.30
+	Hs
		710575 EPHA2_HUMAN (4-789): 0: 587: 19.52		AGAP1_HUMAN (361-662): 3.34e-62: 230: 28.30
+	Hs
		412280 NTRK1_HUMAN (135-751): 2.17e-160: 487: 26.53		DP13B_HUMAN (45-453): 5.6e-98: 327: 16.03
+	Hs
		1157106 NTRK3_HUMAN (159-751): 2.57e-165: 501: 25.24		DP13A_HUMAN (45-456): 7.83e-92: 312: 16.39
+	Hs
		1159553 NTRK2_HUMAN (114-757): 1.02e-163: 496: 25.84		DP13A_HUMAN (45-456): 7.83e-92: 312: 16.39
+	Hs
		541612 FGFR1_HUMAN (3-794): 0: 714: 54.76		SMAP2_HUMAN (436-549): 5.12e-16: 84: 36.21
+	Hs
		931874 EPHA5_HUMAN (4-771): 0: 615: 18.43		SMAP2_HUMAN (436-549): 5.12e-16: 84: 36.21