HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 551
+	Hs
		650710 RFA1_HUMAN (1-616): 0: 781: 100.00		SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93
+	Hs
		651685 RFA1_HUMAN (1-616): 0: 781: 100.00		CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82
+	Hs
		650711 RFA1_HUMAN (1-616): 0: 781: 100.00		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		651110 RFA1_HUMAN (1-616): 0: 781: 100.00		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Hs
		516368 RFA1_HUMAN (1-616): 0: 781: 100.00		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		651383 RFA1_HUMAN (1-616): 0: 781: 100.00		TGO1_HUMAN (138-380): 8.27e-13: 73.8: 25.18
+	Hs
		650764 RFA1_HUMAN (1-616): 0: 781: 100.00		SC24C_HUMAN (233-440): 1.79e-12: 72.2: 17.05
+	Hs
		652107 RFA1_HUMAN (1-616): 0: 781: 100.00		DIDO1_HUMAN (164-416): 4.81e-09: 61.5: 21.59
+	Hs
		652184 RFA1_HUMAN (1-616): 0: 781: 100.00		WDR33_HUMAN (180-396): 5.21e-09: 61.5: 24.69
+	Hs
		652459 RFA1_HUMAN (1-616): 0: 781: 100.00		OGFR_HUMAN (170-417): 4.4e-09: 61.1: 21.76