HitPredict

Interactor 1: H2B1O (P23527)
Histone H2B type 1-O (H2B-clustered histone 17) (Histone H2B.2) (Histone H2B.n) (H2B/n)
Gene: H2BC17

Interactor 2: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 480
+	Mm
		728522 H2B2B_MOUSE (1-126): 1.28e-55: 171: 98.41		AKT1_MOUSE (1-480): 0: 590: 98.33
+	Mm
		728524 H2B1C_MOUSE (1-126): 7.91e-55: 169: 98.41		AKT1_MOUSE (1-480): 0: 590: 98.33
+	Hs
		449681 H2B1J_HUMAN (1-126): 5.51e-55: 169: 98.41		AKT1_HUMAN (1-480): 0: 589: 100.00
+	Hs
		728272 H2B2E_HUMAN (1-126): 4.94e-55: 169: 99.21		AKT1_HUMAN (1-480): 0: 589: 100.00
+	Hs
		728056 H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62		AKT1_HUMAN (1-480): 0: 589: 100.00
+	Hs
		659864 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		AKT2_HUMAN (1-477): 0: 562: 81.21
+	Hs
		449682 H2B1J_HUMAN (1-126): 5.51e-55: 169: 98.41		AKT2_HUMAN (1-477): 0: 562: 81.21
+	Hs
		728593 H2B2E_HUMAN (1-126): 4.94e-55: 169: 99.21		AKT2_HUMAN (1-477): 0: 562: 81.21
+	Hs
		436579 H2B1J_HUMAN (1-126): 5.51e-55: 169: 98.41		KPCB_HUMAN (14-479): 1.32e-148: 441: 35.46
+	Hs
		436637 H2BFS_HUMAN (1-126): 8.83e-55: 169: 96.03		KPCB_HUMAN (14-479): 1.32e-148: 441: 35.46
+	Hs
		436645 H2B1C_HUMAN (1-126): 7.91e-55: 169: 98.41		KPCB_HUMAN (14-479): 1.32e-148: 441: 35.46
+	Hs
		436679 H2B2E_HUMAN (1-126): 4.94e-55: 169: 99.21		KPCB_HUMAN (14-479): 1.32e-148: 441: 35.46
+	Hs
		436721 H2B1M_HUMAN (1-126): 3.33e-55: 169: 95.24		KPCB_HUMAN (14-479): 1.32e-148: 441: 35.46
+	Hs
		436619 H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62		KPCB_HUMAN (14-479): 1.32e-148: 441: 35.46
+	Hs
		605772 H2B1H_HUMAN (1-126): 3.4e-55: 169: 99.21		KAPCA_HUMAN (138-445): 7.79e-145: 420: 42.53
+	Hs
		651697 H2B1H_HUMAN (1-126): 3.4e-55: 169: 99.21		KAPCB_HUMAN (140-445): 3.08e-144: 418: 43.14
+	Hs
		651619 H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62		KAPCB_HUMAN (140-445): 3.08e-144: 418: 43.14
+	Hs
		659874 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		KS6A3_HUMAN (36-455): 4.73e-103: 325: 23.01
+	Hs
		449691 H2B1J_HUMAN (1-126): 5.51e-55: 169: 98.41		KS6A3_HUMAN (36-455): 4.73e-103: 325: 23.01
+	Hs
		908123 H2B2E_HUMAN (1-126): 4.94e-55: 169: 99.21		KS6A3_HUMAN (36-455): 4.73e-103: 325: 23.01