HitPredict

Interactor 1: TNR16 (P08138)
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (Low-affinity nerve growth factor receptor p75NGFR) (Low-affinity nerve growth factor receptor p75NGR) (p75 ICD) (CD antigen CD271)
Gene: NGFR

Interactor 2: TRAF1 (Q13077)
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene: TRAF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10514511
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 427 Hs			1 416
+	Hs
		584392 TNR1A_HUMAN (29-417): 1.27e-76: 247: 18.27		TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00
+	Hs
		436618 TNR16_HUMAN (1-427): 1.17e-115: 346: 100.00		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Rn
		78206 TNR16_RAT (3-427): 3.25e-110: 332: 92.24		B5DFH7_RAT (3-415): 2.07e-119: 358: 36.82
+	Hs
		436651 TNR16_HUMAN (1-427): 1.17e-115: 346: 100.00		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Hs
		591319 TNR1B_HUMAN (8-274): 1.53e-45: 165: 18.32		TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00
+	Rn
		78177 TNR16_RAT (3-427): 3.25e-110: 332: 92.24		TRAF6_RAT (15-414): 4.07e-99: 307: 22.08
+	Mm
		626852 TNR1A_MOUSE (29-425): 1.22e-78: 252: 17.33		TRAF2_MOUSE (3-415): 3.91e-127: 378: 37.77
+	Hs
		584390 TNR1A_HUMAN (29-417): 1.27e-76: 247: 18.27		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		154352 TR10B_HUMAN (17-424): 1.06e-61: 207: 16.08		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		1020849 TNR25_HUMAN (29-422): 1.33e-58: 198: 18.75		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		584509 TNR1A_HUMAN (29-417): 1.27e-76: 247: 18.27		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Mm
		648951 TNR5_MOUSE (13-254): 3.01e-46: 162: 23.90		TRAF2_MOUSE (3-415): 3.91e-127: 378: 37.77
+	Hs
		591317 TNR1B_HUMAN (8-274): 1.53e-45: 165: 18.32		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		591438 TNR1B_HUMAN (8-274): 1.53e-45: 165: 18.32		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Mm
		648955 TNR5_MOUSE (13-254): 3.01e-46: 162: 23.90		TRAF6_MOUSE (15-414): 1.94e-101: 313: 22.51
+	Hs
		129526 TNR16_HUMAN (1-427): 1.17e-115: 346: 100.00		TRAF5_HUMAN (14-261): 1.36e-16: 83.8: 13.91
+	Hs
		436620 TNR16_HUMAN (1-427): 1.17e-115: 346: 100.00		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77
+	Hs
		436641 TNR16_HUMAN (1-427): 1.17e-115: 346: 100.00		TRAF4_HUMAN (27-136): 3.55e-09: 60.3: 17.86
+	Hs
		584394 TNR1A_HUMAN (29-417): 1.27e-76: 247: 18.27		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77
+	Hs
		591320 TNR1B_HUMAN (8-274): 1.53e-45: 165: 18.32		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77