HitPredict

Interactor 1: PO2F1 (P25425)
POU domain, class 2, transcription factor 1 (NF-A1) (Octamer-binding protein 1) (Oct-1) (Octamer-binding transcription factor 1) (OTF-1)
Gene: Pou2f1

Interactor 2: HXC4 (Q08624)
Homeobox protein Hox-C4 (Homeobox protein Hox-3.5)
Gene: Hoxc4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.80	0.625

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain, Homeodomain~Pou
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 770 Mm			1 264
+	Hs
		478311 PO2F1_HUMAN (1-770): 3.87e-82: 279: 87.55		HXC4_HUMAN (1-264): 3.9e-56: 182: 98.86
+	Mm
		479039 PO2F1_MOUSE (1-770): 1.18e-95: 316: 100.00		HXA6_MOUSE (8-233): 7.85e-39: 137: 31.78
+	Mm
		484849 PO2F1_MOUSE (1-770): 1.18e-95: 316: 100.00		HXB8_MOUSE (3-248): 1.03e-33: 124: 27.45
+	Hs
		576197 PO2F1_HUMAN (1-770): 3.87e-82: 279: 87.55		GSC_HUMAN (19-251): 2.42e-34: 126: 15.45
+	Dm
		84569 B7YZU0_DROME (200-449): 8.07e-49: 188: 27.94		UBX_DROME (19-217): 1.47e-29: 116: 27.05
+	Hs
		725037 PO6F2_HUMAN (75-454): 5.7e-47: 180: 22.82		HXC8_HUMAN (3-224): 1.58e-31: 118: 24.79
+	Hs
		1007908 PO6F2_HUMAN (75-454): 5.7e-47: 180: 22.82		HXC5_HUMAN (3-223): 2.3e-30: 114: 36.96
+	Ce
		836725 HM18_CAEEL (130-496): 1.9e-47: 178: 29.54		Q22459_CAEEL (148-264): 1.75e-29: 112: 25.64
+	Dm
		84567 B7YZU0_DROME (200-449): 8.07e-49: 188: 27.94		ABDA_DROME (152-216): 3.54e-21: 94.4: 75.39
+	Hs
		685126 PAX6_HUMAN (352-572): 2.06e-42: 161: 22.69		HXA1_HUMAN (20-229): 1.31e-31: 120: 29.49
+	Hs
		685112 PAX6_HUMAN (352-572): 2.06e-42: 161: 22.69		HXC8_HUMAN (3-224): 1.58e-31: 118: 24.79
+	Dm
		593557 CF1A_DROME (90-498): 8.83e-40: 154: 28.36		UBX_DROME (19-217): 1.47e-29: 116: 27.05
+	Hs
		70964 PO4F2_HUMAN (170-442): 2.41e-36: 143: 28.42		NOTO_HUMAN (21-247): 2.07e-29: 113: 21.15
+	Dm
		593556 CF1A_DROME (90-498): 8.83e-40: 154: 28.36		ABDA_DROME (152-216): 3.54e-21: 94.4: 75.39
+	Hs
		725030 LHX2_HUMAN (352-495): 4.3e-13: 73.8: 24.00		HXC8_HUMAN (3-224): 1.58e-31: 118: 24.79
+	Hs
		942436 ZFHX3_HUMAN (358-594): 1.04e-09: 64.4: 13.16		GSC_HUMAN (19-251): 2.42e-34: 126: 15.45
+	Hs
		942447 ZFHX4_HUMAN (330-467): 3.87e-09: 62.5: 24.64		GSC_HUMAN (19-251): 2.42e-34: 126: 15.45