HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: TPD53 (Q16890)
Tumor protein D53 (hD53) (Tumor protein D52-like 1)
Gene: TPD52L1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.644

Property	Details
Experiments	24255178, 12963375
Identification Methods	affinity chromatography technology, pull down, coimmunoprecipitation, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 246 Hs			1 204
+	Hs
		927097 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		TPD53_HUMAN (1-204): 2.75e-72: 219: 100.00
+	Hs
		878024 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		TPD52_HUMAN (4-199): 8.9e-60: 188: 53.06
+	Hs
		646935 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		TPD53_HUMAN (1-204): 2.75e-72: 219: 100.00
+	Hs
		646753 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		TPD52_HUMAN (4-199): 8.9e-60: 188: 53.06
+	Hs
		904620 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		TPD53_HUMAN (1-204): 2.75e-72: 219: 100.00
+	Hs
		982055 1433F_HUMAN (4-244): 2.7e-107: 311: 75.51		TPD53_HUMAN (1-204): 2.75e-72: 219: 100.00
+	Dm
		55798 1433Z_DROME (2-246): 4.79e-141: 396: 78.78		A1ZB77_DROME (15-163): 1.15e-37: 130: 26.67
+	Hs
		684065 1433S_HUMAN (3-239): 3.38e-100: 293: 68.62		TPD53_HUMAN (1-204): 2.75e-72: 219: 100.00
+	Hs
		202723 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		TPD54_HUMAN (45-194): 9.53e-38: 131: 43.53