HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: FRMD5 (Q7Z6J6)
FERM domain-containing protein 5
Gene: FRMD5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24366813
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 570
+	Hs
		663970 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN4_HUMAN (4-474): 5.62e-141: 433: 26.85
+	Hs
		663962 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN4_HUMAN (4-474): 5.62e-141: 433: 26.85
+	Hs
		910025 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		E41L1_HUMAN (3-496): 7.52e-141: 431: 27.54
+	Hs
		204644 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		E41L2_HUMAN (3-498): 2.96e-139: 430: 30.15
+	Hs
		683710 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L1_HUMAN (3-496): 7.52e-141: 431: 27.54
+	Hs
		204620 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L2_HUMAN (3-498): 2.96e-139: 430: 30.15
+	Hs
		663973 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PTN4_HUMAN (4-474): 5.62e-141: 433: 26.85
+	Hs
		505612 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		EPB41_HUMAN (3-495): 9.68e-139: 425: 28.63
+	Hs
		927524 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		E41L1_HUMAN (3-496): 7.52e-141: 431: 27.54
+	Hs
		204648 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		E41L2_HUMAN (3-498): 2.96e-139: 430: 30.15
+	Hs
		683735 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L5_HUMAN (13-495): 1.07e-138: 421: 29.48
+	Hs
		910185 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		E41L3_HUMAN (9-481): 7.89e-132: 413: 30.21
+	Hs
		683836 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L3_HUMAN (9-481): 7.89e-132: 413: 30.21
+	Hs
		927682 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		E41L3_HUMAN (9-481): 7.89e-132: 413: 30.21
+	Hs
		204614 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		E41L2_HUMAN (3-498): 2.96e-139: 430: 30.15
+	Hs
		640229 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN3_HUMAN (4-421): 8.58e-118: 372: 27.19
+	Hs
		640216 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN3_HUMAN (4-421): 8.58e-118: 372: 27.19
+	Hs
		640230 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PTN3_HUMAN (4-421): 8.58e-118: 372: 27.19
+	Hs
		640086 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MOES_HUMAN (13-505): 3.72e-119: 366: 18.10
+	Hs
		547003 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		EZRI_HUMAN (13-474): 3.25e-113: 350: 21.22