HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: CDK3 (Q00526)
Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)
Gene: CDK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 305
+	Hs
		909447 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CDK3_HUMAN (1-305): 1.8e-151: 427: 100.00
+	Hs
		414774 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		CDK1_HUMAN (1-290): 1.16e-137: 392: 65.98
+	Hs
		625306 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CDK2_HUMAN (1-292): 1.87e-148: 420: 76.71
+	Hs
		683966 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		CDK17_HUMAN (1-291): 6.26e-124: 365: 53.43
+	Hs
		625334 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		CDK2_HUMAN (1-292): 1.87e-148: 420: 76.71
+	Hs
		909449 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CDK17_HUMAN (1-291): 6.26e-124: 365: 53.43
+	Hs
		841132 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CDK7_HUMAN (3-296): 2.86e-124: 360: 45.64
+	Hs
		683965 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		CDK16_HUMAN (1-288): 4.21e-108: 324: 54.33
+	Hs
		926925 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		CDK17_HUMAN (1-291): 6.26e-124: 365: 53.43
+	Hs
		841150 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		CDK7_HUMAN (3-296): 2.86e-124: 360: 45.64
+	Hs
		646799 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		CDK3_HUMAN (1-305): 1.8e-151: 427: 100.00
+	Hs
		909448 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CDK16_HUMAN (1-288): 4.21e-108: 324: 54.33
+	Hs
		625130 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		CDK2_HUMAN (1-292): 1.87e-148: 420: 76.71
+	Hs
		683268 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		CDK3_HUMAN (1-305): 1.8e-151: 427: 100.00
+	Hs
		926924 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		CDK16_HUMAN (1-288): 4.21e-108: 324: 54.33
+	Hs
		646801 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		CDK17_HUMAN (1-291): 6.26e-124: 365: 53.43
+	Hs
		646734 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		CDK7_HUMAN (3-296): 2.86e-124: 360: 45.64
+	Hs
		683213 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		CDK7_HUMAN (3-296): 2.86e-124: 360: 45.64
+	Hs
		646800 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		CDK16_HUMAN (1-288): 4.21e-108: 324: 54.33
+	Hs
		683269 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		CDK16_HUMAN (1-288): 4.21e-108: 324: 54.33