HitPredict

Interactor 1: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Interactor 2: SNTB1 (Q13884)
Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43)
Gene: SNTB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36976175
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, PH~PK_Tyr_Ser-Thr, PDZ~SAM_1
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 976 Hs			1 538
+	Hs
		168639 EPHA2_HUMAN (1-976): 0: 1124: 100.00		CSKP_HUMAN (71-512): 1.9e-66: 233: 10.71
+	Hs
		710528 EPHA2_HUMAN (1-976): 0: 1124: 100.00		PALS2_HUMAN (6-474): 3.38e-68: 230: 11.59
+	Hs
		168694 EPHA7_HUMAN (4-974): 0: 1120: 50.15		CSKP_HUMAN (71-512): 1.9e-66: 233: 10.71
+	Hs
		168659 EPHA4_HUMAN (1-974): 0: 1110: 50.35		CSKP_HUMAN (71-512): 1.9e-66: 233: 10.71
+	Hs
		710508 EPHA2_HUMAN (1-976): 0: 1124: 100.00		GOPC_HUMAN (83-258): 5.23e-30: 124: 31.64
+	Hs
		1147439 EPHA7_HUMAN (4-974): 0: 1120: 50.15		GOPC_HUMAN (83-258): 5.23e-30: 124: 31.64
+	Hs
		931902 EPHA5_HUMAN (11-976): 0: 1115: 51.34		GOPC_HUMAN (83-258): 5.23e-30: 124: 31.64
+	Hs
		1147448 EPHA7_HUMAN (4-974): 0: 1120: 50.15		LIN7C_HUMAN (108-197): 5.01e-30: 118: 42.22
+	Hs
		932138 EPHA4_HUMAN (1-974): 0: 1110: 50.35		GOPC_HUMAN (83-258): 5.23e-30: 124: 31.64
+	Hs
		931905 EPHA5_HUMAN (11-976): 0: 1115: 51.34		LIN7C_HUMAN (108-197): 5.01e-30: 118: 42.22
+	Hs
		932143 EPHA4_HUMAN (1-974): 0: 1110: 50.35		LIN7C_HUMAN (108-197): 5.01e-30: 118: 42.22
+	Hs
		710208 EPHA2_HUMAN (1-976): 0: 1124: 100.00		DLG1_HUMAN (43-203): 1.38e-20: 98.1: 24.70
+	Hs
		710664 EPHA3_HUMAN (24-976): 0: 1096: 50.98		GOPC_HUMAN (83-258): 5.23e-30: 124: 31.64
+	Hs
		1091501 EPHA7_HUMAN (4-974): 0: 1120: 50.15		DLG1_HUMAN (43-203): 1.38e-20: 98.1: 24.70
+	Hs
		710408 EPHA2_HUMAN (1-976): 0: 1124: 100.00		DLG3_HUMAN (37-383): 4.25e-18: 90: 14.44
+	Hs
		931842 EPHA5_HUMAN (11-976): 0: 1115: 51.34		DLG1_HUMAN (43-203): 1.38e-20: 98.1: 24.70
+	Hs
		932062 EPHA4_HUMAN (1-974): 0: 1110: 50.35		DLG1_HUMAN (43-203): 1.38e-20: 98.1: 24.70
+	Hs
		710588 EPHA2_HUMAN (1-976): 0: 1124: 100.00		GRIP1_HUMAN (107-193): 2.55e-11: 68.7: 30.34
+	Hs
		932093 EPHA4_HUMAN (1-974): 0: 1110: 50.35		MAGI2_HUMAN (63-260): 3.86e-11: 67.9: 13.30
+	Mm
		932046 EPHB2_MOUSE (28-973): 0: 1078: 48.29		GRIP1_MOUSE (50-233): 8.68e-11: 66.8: 19.90