HitPredict

Interactor 1: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Interactor 2: RAI14 (Q9P0K7)
Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14)
Gene: RAI14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	36976175
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~fn3
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 976 Hs			1 980
+	Hs
		710348 EPHA2_HUMAN (1-976): 0: 1124: 100.00		MIB1_HUMAN (12-269): 2.36e-67: 246: 28.25
+	Hs
		710207 EPHA2_HUMAN (1-976): 0: 1124: 100.00		ANK3_HUMAN (60-412): 3.93e-42: 170: 21.25
+	Hs
		710469 EPHA2_HUMAN (1-976): 0: 1124: 100.00		UACA_HUMAN (411-974): 2.31e-39: 161: 24.63
+	Hs
		710562 EPHA2_HUMAN (1-976): 0: 1124: 100.00		ANR50_HUMAN (67-280): 1.06e-34: 146: 23.36
+	Hs
		710822 EPHB2_HUMAN (28-973): 0: 1077: 48.29		ANK3_HUMAN (60-412): 3.93e-42: 170: 21.25
+	Hs
		710561 EPHA2_HUMAN (1-976): 0: 1124: 100.00		KDIS_HUMAN (127-370): 2.85e-25: 115: 18.44
+	Hs
		710889 EPHB2_HUMAN (28-973): 0: 1077: 48.29		UACA_HUMAN (411-974): 2.31e-39: 161: 24.63
+	Hs
		931913 EPHA5_HUMAN (11-976): 0: 1115: 51.34		KDIS_HUMAN (127-370): 2.85e-25: 115: 18.44
+	Hs
		710670 EPHA3_HUMAN (24-976): 0: 1096: 50.98		KDIS_HUMAN (127-370): 2.85e-25: 115: 18.44
+	Hs
		710191 EPHA2_HUMAN (1-976): 0: 1124: 100.00		NOTC2_HUMAN (10-123): 1.43e-14: 81.1: 22.61
+	Hs
		1047552 EPHA7_HUMAN (4-974): 0: 1120: 50.15		NOTC2_HUMAN (10-123): 1.43e-14: 81.1: 22.61
+	Hs
		931837 EPHA5_HUMAN (11-976): 0: 1115: 51.34		NOTC2_HUMAN (10-123): 1.43e-14: 81.1: 22.61
+	Hs
		932057 EPHA4_HUMAN (1-974): 0: 1110: 50.35		NOTC2_HUMAN (10-123): 1.43e-14: 81.1: 22.61
+	Hs
		710815 EPHB2_HUMAN (28-973): 0: 1077: 48.29		NOTC2_HUMAN (10-123): 1.43e-14: 81.1: 22.61
+	Hs
		640132 EPHA1_HUMAN (17-967): 0: 947: 49.28		DAPK1_HUMAN (111-429): 3.3e-31: 134: 11.91
+	Hs
		439627 INSR_HUMAN (281-911): 2.91e-136: 444: 24.78		POTEJ_HUMAN (16-586): 1.59e-64: 238: 18.67
+	Hs
		506922 FGFR3_HUMAN (381-889): 3.37e-136: 430: 24.65		POTEI_HUMAN (16-586): 1.27e-65: 242: 18.50
+	Hs
		720361 UFO_HUMAN (294-911): 1.96e-144: 454: 24.15		KDIS_HUMAN (127-370): 2.85e-25: 115: 18.44
+	Hs
		650314 FGFR3_HUMAN (381-889): 3.37e-136: 430: 24.65		FANK1_HUMAN (156-276): 6.26e-12: 70: 21.31
+	Hs
		463472 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		NOTC2_HUMAN (10-123): 1.43e-14: 81.1: 22.61