HitPredict

Interactor 1: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Interactor 2: KDIS (Q9ULH0)
Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)
Gene: KIDINS220

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.675

Property	Details
Experiments	35384245, 36976175
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~fn3
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 976 Hs			1 1771
+	Hs
		931913 EPHA5_HUMAN (11-976): 0: 1115: 51.34		KDIS_HUMAN (13-1771): 0: 2597: 100.00
+	Hs
		710670 EPHA3_HUMAN (24-976): 0: 1096: 50.98		KDIS_HUMAN (13-1771): 0: 2597: 100.00
+	Hs
		720361 UFO_HUMAN (294-911): 1.96e-144: 454: 24.15		KDIS_HUMAN (13-1771): 0: 2597: 100.00
+	Hs
		463835 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		KDIS_HUMAN (13-1771): 0: 2597: 100.00
+	Hs
		710562 EPHA2_HUMAN (1-976): 0: 1124: 100.00		ANR50_HUMAN (173-499): 1.65e-67: 254: 18.37
+	Hs
		710207 EPHA2_HUMAN (1-976): 0: 1124: 100.00		ANK3_HUMAN (240-506): 3.83e-62: 238: 21.84
+	Hs
		710812 EPHB2_HUMAN (28-973): 0: 1077: 48.29		ANK2_HUMAN (234-506): 1.27e-62: 240: 18.89
+	Hs
		710822 EPHB2_HUMAN (28-973): 0: 1077: 48.29		ANK3_HUMAN (240-506): 3.83e-62: 238: 21.84
+	Hs
		640288 EPHA1_HUMAN (17-967): 0: 947: 49.28		TNKS2_HUMAN (2-285): 7.82e-72: 266: 27.27
+	Hs
		332386 EPHA1_HUMAN (17-967): 0: 947: 49.28		TNKS1_HUMAN (2-227): 2.93e-56: 218: 23.76
+	Hs
		640132 EPHA1_HUMAN (17-967): 0: 947: 49.28		DAPK1_HUMAN (4-305): 4.94e-35: 149: 31.58
+	Hs
		463836 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		ANR50_HUMAN (173-499): 1.65e-67: 254: 18.37
+	Hs
		463458 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		ANK2_HUMAN (234-506): 1.27e-62: 240: 18.89
+	Hs
		463487 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		ANK3_HUMAN (240-506): 3.83e-62: 238: 21.84