HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: KDIS (Q9ULH0)
Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)
Gene: KIDINS220

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.578

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~fn3
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 894 Hs			1 1771
+	Hs
		710670 EPHA3_HUMAN (2-810): 0: 656: 19.95		KDIS_HUMAN (13-1771): 0: 2597: 100.00
+	Hs
		931913 EPHA5_HUMAN (2-812): 0: 625: 20.50		KDIS_HUMAN (13-1771): 0: 2597: 100.00
+	Hs
		710561 EPHA2_HUMAN (1-843): 0: 616: 19.51		KDIS_HUMAN (13-1771): 0: 2597: 100.00
+	Hs
		641281 FGFR2_HUMAN (17-859): 1.11e-164: 502: 21.57		KDIS_HUMAN (13-1771): 0: 2597: 100.00
+	Hs
		761308 RYK_HUMAN (521-810): 4.47e-57: 209: 37.63		KDIS_HUMAN (13-1771): 0: 2597: 100.00
+	Hs
		710562 EPHA2_HUMAN (1-843): 0: 616: 19.51		ANR50_HUMAN (173-499): 1.65e-67: 254: 18.37
+	Hs
		710812 EPHB2_HUMAN (2-821): 0: 618: 19.70		ANK2_HUMAN (234-506): 1.27e-62: 240: 18.89
+	Hs
		710822 EPHB2_HUMAN (2-821): 0: 618: 19.70		ANK3_HUMAN (240-506): 3.83e-62: 238: 21.84
+	Hs
		710207 EPHA2_HUMAN (1-843): 0: 616: 19.51		ANK3_HUMAN (240-506): 3.83e-62: 238: 21.84
+	Hs
		640288 EPHA1_HUMAN (1-843): 0: 561: 20.38		TNKS2_HUMAN (2-285): 7.82e-72: 266: 27.27
+	Hs
		332386 EPHA1_HUMAN (1-843): 0: 561: 20.38		TNKS1_HUMAN (2-227): 2.93e-56: 218: 23.76
+	Hs
		640132 EPHA1_HUMAN (1-843): 0: 561: 20.38		DAPK1_HUMAN (4-305): 4.94e-35: 149: 31.58
+	Mm
		109254 MET_MOUSE (536-799): 5.49e-66: 243: 45.90		ANK3_MOUSE (240-506): 5.54e-63: 240: 22.18
+	Hs
		541441 FGFR1_HUMAN (505-815): 6.73e-56: 209: 40.12		ANK2_HUMAN (234-506): 1.27e-62: 240: 18.89
+	Hs
		541458 FGFR1_HUMAN (505-815): 6.73e-56: 209: 40.12		ANK3_HUMAN (240-506): 3.83e-62: 238: 21.84
+	Hs
		761215 RYK_HUMAN (521-810): 4.47e-57: 209: 37.63		ANK3_HUMAN (240-506): 3.83e-62: 238: 21.84
+	Hs
		541315 FGFR1_HUMAN (505-815): 6.73e-56: 209: 40.12		ANK1_HUMAN (271-530): 2.48e-47: 189: 19.08
+	Hs
		1051020 FAK1_HUMAN (527-851): 1.73e-56: 213: 36.83		ANKH1_HUMAN (359-505): 4.26e-23: 110: 12.16