HitPredict

Interactor 1: RFA3 (P35244)
Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3)
Gene: RPA3

Interactor 2: RFA4 (Q13156)
Replication protein A 30 kDa subunit (RP-A p30) (Replication factor A protein 4) (RF-A protein 4)
Gene: RPA4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.707

The method score is based on:

Property	Details
Experiments	26186194, 28514442, 7760808, 33961781
Identification Methods	affinity chromatography technology, two hybrid, cosedimentation in solution, coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0003697 - single-stranded DNA binding GO:0005654 - nucleoplasm GO:0005662 - DNA replication factor A complex GO:0006260 - DNA replication and 3 others more... GO:0006281 - DNA repair GO:0006289 - nucleotide-excision repair GO:0035861 - site of double-strand break
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	121
Hs

1	261

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024