HitPredict

Interactor 1: LTK (P29376)
Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)
Gene: LTK

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 864 Hs			1 1025
+	Hs
		711918 LTK_HUMAN (1-864): 0: 766: 100.00		DLG5_HUMAN (647-1019): 8.92e-54: 207: 21.61
+	Hs
		1351403 ALK_HUMAN (4-851): 0: 701: 54.51		DLG5_HUMAN (647-1019): 8.92e-54: 207: 21.61
+	Hs
		1437684 ALK_HUMAN (4-851): 0: 701: 54.51		PKHA5_HUMAN (318-1019): 2.96e-36: 151: 13.24
+	Hs
		641200 FGFR2_HUMAN (222-833): 7.86e-138: 431: 20.62		MPRIP_HUMAN (1-1025): 9.69e-126: 410: 100.00
+	Hs
		1462005 ALK_HUMAN (4-851): 0: 701: 54.51		PKHA6_HUMAN (356-581): 1.7e-31: 135: 24.49
+	Hs
		1217576 ALK_HUMAN (4-851): 0: 701: 54.51		MRCKA_HUMAN (418-981): 1.19e-30: 133: 12.40
+	Hs
		773304 ALK_HUMAN (4-851): 0: 701: 54.51		MYH10_HUMAN (242-1024): 1.66e-21: 103: 8.45
+	Hs
		773080 ALK_HUMAN (4-851): 0: 701: 54.51		MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35
+	Hs
		541606 FGFR1_HUMAN (221-839): 2.46e-139: 435: 20.32		DLG5_HUMAN (647-1019): 8.92e-54: 207: 21.61
+	Hs
		641219 FGFR2_HUMAN (222-833): 7.86e-138: 431: 20.62		DLG5_HUMAN (647-1019): 8.92e-54: 207: 21.61
+	Hs
		650388 FGFR3_HUMAN (100-834): 2.09e-138: 432: 20.89		SCAPE_HUMAN (71-938): 5.41e-44: 176: 13.60
+	Hs
		541549 FGFR1_HUMAN (221-839): 2.46e-139: 435: 20.32		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		640292 EPHA1_HUMAN (25-817): 3.82e-139: 439: 19.11		PKHA5_HUMAN (318-1019): 2.96e-36: 151: 13.24
+	Hs
		541693 FGFR1_HUMAN (221-839): 2.46e-139: 435: 20.32		PKHA5_HUMAN (318-1019): 2.96e-36: 151: 13.24
+	Hs
		640336 EPHA1_HUMAN (25-817): 3.82e-139: 439: 19.11		PKHA6_HUMAN (356-581): 1.7e-31: 135: 24.49
+	Hs
		270766 FGFR1_HUMAN (221-839): 2.46e-139: 435: 20.32		ROCK2_HUMAN (446-1018): 5.24e-17: 88.7: 11.81
+	Hs
		541498 FGFR1_HUMAN (221-839): 2.46e-139: 435: 20.32		PLEC_HUMAN (499-978): 3.11e-11: 70.1: 14.96
+	Hs
		640287 EPHA1_HUMAN (25-817): 3.82e-139: 439: 19.11		TARA_HUMAN (645-1023): 9.99e-10: 65.1: 12.98
+	Hs
		271666 EPHA1_HUMAN (25-817): 3.82e-139: 439: 19.11		HIP1R_HUMAN (626-929): 1.25e-09: 64.5: 19.56
+	Hs
		541680 FGFR1_HUMAN (221-839): 2.46e-139: 435: 20.32		TARA_HUMAN (645-1023): 9.99e-10: 65.1: 12.98