HitPredict

Interactor 1: B2XCM0 (B2XCM0)
Appl2 (DCC-interacting protein 13-beta)
Gene: appl2

Interactor 2: Q7ZVP2 (Q7ZVP2)
small monomeric GTPase (EC 3.6.5.2)
Gene: rab5c

Species: Danio rerio

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	18455989
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005768 - endosome GO:0031901 - early endosome membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 662 Dr			1 221
+	Hs
		592385 DP13B_HUMAN (1-662): 0: 727: 68.97		RAB5A_HUMAN (1-218): 6.55e-89: 262: 80.73
+	Hs
		844630 DP13B_HUMAN (1-662): 0: 727: 68.97		RAB5C_HUMAN (1-218): 4.68e-86: 255: 87.62
+	Hs
		914226 DP13B_HUMAN (1-662): 0: 727: 68.97		RB11A_HUMAN (12-217): 4.7e-86: 255: 38.97
+	Hs
		1243524 DP13B_HUMAN (1-662): 0: 727: 68.97		RB22A_HUMAN (22-193): 5.12e-62: 193: 52.00
+	Hs
		592569 DP13A_HUMAN (1-662): 0: 653: 49.65		RAB5A_HUMAN (1-218): 6.55e-89: 262: 80.73
+	Dr
		71371 B2XCL9_DANRE (1-662): 0: 647: 47.96		Q7ZVP2_DANRE (1-221): 6.75e-89: 262: 100.00
+	Hs
		1356440 DP13A_HUMAN (1-662): 0: 653: 49.65		RB22A_HUMAN (22-193): 5.12e-62: 193: 52.00
+	Hs
		1356439 DP13A_HUMAN (1-662): 0: 653: 49.65		RAB21_HUMAN (23-220): 2.96e-52: 169: 43.20
+	Hs
		592263 ACAP2_HUMAN (7-462): 4.63e-123: 385: 21.01		RAB5A_HUMAN (1-218): 6.55e-89: 262: 80.73
+	Ce
		954792 CNT1_CAEEL (1-462): 1.9e-108: 348: 15.59		P91857_CAEEL (7-217): 3.36e-97: 283: 74.65
+	Ce
		1276018 CNT1_CAEEL (1-462): 1.9e-108: 348: 15.59		RAB10_CAEEL (18-217): 2.43e-95: 278: 35.50
+	Mm
		1186345 ASAP2_MOUSE (19-462): 1.35e-95: 317: 17.17		RAB1B_MOUSE (15-217): 3.64e-89: 262: 41.87
+	Dm
		185683 Q7KS50_DROME (251-462): 1.15e-38: 153: 22.17		O18335_DROME (12-217): 8.79e-85: 252: 38.03