HitPredict

Interactor 1: ITPR (P29993)
Inositol 1,4,5-trisphosphate receptor (InsP3 receptor) (IP3R) (InsP3R)
Gene: ITPR

Interactor 2: ITPR (P29993)
Inositol 1,4,5-trisphosphate receptor (InsP3 receptor) (IP3R) (InsP3R)
Gene: ITPR

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16325255
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ins145_P3_rec~Ins145_P3_rec, Ins145_P3_rec~MIR, Ins145_P3_rec~RIH_assoc, Ins145_P3_rec~RYDR_ITPR, Ion_trans~Ion_trans, MIR~MIR, MIR~RYDR_ITPR, RYDR_ITPR~RYDR_ITPR
Common GO terms GO:0000280 - nuclear division
GO:0005220 - inositol 1,4,5-trisphosphate-gated calcium channel activity
GO:0005509 - calcium ion binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
and 29 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 2838
Dm

1 2838
+ Hs
+ Hs
+ Mm
+ Rn
+ Hs
+ Ce
+ Oc
+ Hs
+ Hs
+ Mm
+ Oc
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025