HitPredict

Interactor 1: PSB5 (P30656)
Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain subunit PRE2) (Multicatalytic endopeptidase complex subunit PRE2) (Proteasome component PRE2) (Proteinase YSCE subunit PRE2)
Gene: PRE2

Interactor 2: PSA4 (P40303)
Proteasome subunit alpha type-4 (Macropain subunit PRE6) (Multicatalytic endopeptidase complex subunit PRE6) (Proteasome component PRE6) (Proteinase YSCE subunit PRE6)
Gene: PRE6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 17892321, 8628401, 16554755, 16429126, 31848235, 22940862, 14759368, 9799224, 37968396
Identification Methods anti tag coimmunoprecipitation, biochemical, affinity chromatography technology, cross-linking study, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 287
Sc

1 254
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Service provided by Combinatics, Japan

Last updated: 11Aug2025