HitPredict

Interactor 1: SCN4A (P35499)
Sodium channel protein type 4 subunit alpha (SkM1) (Sodium channel protein skeletal muscle subunit alpha) (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4)
Gene: SCN4A

Interactor 2: AGRG6 (Q86SQ4)
Adhesion G-protein coupled receptor G6 (Developmentally regulated G-protein-coupled receptor) (G-protein coupled receptor 126) (Vascular inducible G protein-coupled receptor) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)]
Gene: ADGRG6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1836 Hs			1 1221
+	Hs
		300335 SCN4A_HUMAN (1-1836): 0: 1832: 100.00		AGRL1_HUMAN (517-1219): 1.47e-163: 527: 22.21
+	Hs
		723854 SCN4A_HUMAN (1-1836): 0: 1832: 100.00		AGRE5_HUMAN (541-1167): 2.69e-113: 375: 19.91
+	Hs
		132277 CAC1A_HUMAN (550-765): 6.02e-33: 142: 23.70		AGRL1_HUMAN (517-1219): 1.47e-163: 527: 22.21
+	Hs
		315828 CAC1C_HUMAN (29-324): 8.11e-20: 99.5: 18.67		AGRL2_HUMAN (521-1219): 1.54e-166: 535: 20.96
+	Hs
		300348 CAC1C_HUMAN (29-324): 8.11e-20: 99.5: 18.67		AGRL1_HUMAN (517-1219): 1.47e-163: 527: 22.21
+	Hs
		1047265 CAC1C_HUMAN (29-324): 8.11e-20: 99.5: 18.67		AGRL3_HUMAN (525-1215): 1.82e-159: 515: 23.21
+	Hs
		1047292 CAC1C_HUMAN (29-324): 8.11e-20: 99.5: 18.67		CELR3_HUMAN (518-1160): 5.16e-114: 396: 18.18