HitPredict

Interactor 1: MYH10 (P35580)
Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)
Gene: MYH10

Interactor 2: IKKE (Q14164)
Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)
Gene: IKBKE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	17353931, 14743216
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1976 Hs			1 716
+	Hs
		158414 MYH10_HUMAN (1-1976): 0: 1106: 100.00		IKKB_HUMAN (9-701): 6.33e-128: 399: 18.97
+	Hs
		167487 MYH10_HUMAN (1-1976): 0: 1106: 100.00		IKKA_HUMAN (9-700): 5.05e-116: 367: 18.31
+	Hs
		725223 MYH10_HUMAN (1-1976): 0: 1106: 100.00		MARK4_HUMAN (9-262): 3.68e-86: 289: 28.21
+	Hs
		724823 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		IKKE_HUMAN (1-716): 1.32e-170: 508: 100.00
+	Hs
		167488 MYH11_HUMAN (805-1976): 1.82e-68: 259: 18.21		IKKA_HUMAN (9-700): 5.05e-116: 367: 18.31
+	Hs
		167486 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		IKKA_HUMAN (9-700): 5.05e-116: 367: 18.31
+	Hs
		167573 MYH14_HUMAN (889-1974): 4.36e-57: 221: 18.29		IKKA_HUMAN (9-700): 5.05e-116: 367: 18.31
+	Hs
		724967 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		MARK4_HUMAN (9-262): 3.68e-86: 289: 28.21