HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: MTMR4 (Q9NYA4)
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4 (EC 3.1.3.95) (FYVE domain-containing dual specificity protein phosphatase 2) (FYVE-DSP2) (Myotubularin-related protein 4) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (Zinc finger FYVE domain-containing protein 11)
Gene: MTMR4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.741

Property	Details
Experiments	27432908, 28675297, 33961781, 35271311, 36931259, 28514442, unassigned3799
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1195
+	Hs
		972059 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		MTMR4_HUMAN (1-1195): 0: 1239: 100.00
+	Hs
		990793 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MTMR4_HUMAN (1-1195): 0: 1239: 100.00
+	Hs
		971497 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		MTMR3_HUMAN (1-1195): 0: 1014: 47.63
+	Hs
		729813 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		MTMR3_HUMAN (1-1195): 0: 1014: 47.63
+	Hs
		990194 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MTMR3_HUMAN (1-1195): 0: 1014: 47.63
+	Mm
		990072 1433Z_MOUSE (3-244): 3.15e-142: 399: 88.02		MTMR1_MOUSE (14-625): 0: 721: 28.44
+	Hs
		971496 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		MTMR2_HUMAN (7-608): 0: 714: 33.12
+	Hs
		990790 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MTMRA_HUMAN (6-625): 7.59e-155: 484: 19.89
+	Hs
		331736 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		MTMR5_HUMAN (161-716): 2.02e-135: 456: 22.97
+	Mm
		989993 1433Z_MOUSE (3-244): 3.15e-142: 399: 88.02		MTMR5_MOUSE (161-716): 1e-135: 456: 23.13
+	Hs
		971972 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		MTMRC_HUMAN (6-550): 8.69e-131: 419: 18.87
+	Hs
		730220 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		MTMRC_HUMAN (6-550): 8.69e-131: 419: 18.87
+	Hs
		990703 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MTMRC_HUMAN (6-550): 8.69e-131: 419: 18.87
+	Hs
		971683 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		FGD6_HUMAN (610-1195): 4.81e-77: 281: 14.80
+	Hs
		729980 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		FGD6_HUMAN (610-1195): 4.81e-77: 281: 14.80
+	Hs
		990390 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		FGD6_HUMAN (610-1195): 4.81e-77: 281: 14.80
+	Hs
		971677 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		FGD5_HUMAN (604-1191): 2.86e-72: 266: 14.73
+	Hs
		990481 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		WDFY3_HUMAN (907-1185): 6.65e-57: 219: 21.36
+	Hs
		971915 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		RUFY1_HUMAN (974-1173): 7.34e-41: 163: 27.00
+	Hs
		990641 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		RUFY1_HUMAN (974-1173): 7.34e-41: 163: 27.00